Chika Saegusa
Kanagawa, Japan
Last Updated: 09/26/2026
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Found 13 publications
Modeling Mitochondrial Disease Using Brain Organoids: A Focus on Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke-like Episodes.
Journal: Journal of visualized experiments : JoVE
Published: October 27, 2025
Generation of an induced pluripotent stem cell line (KEIUi008-A) from a hearing loss patient with an A1555G mutation in mitochondrial DNA.
Journal: Stem cell research
Published: March 21, 2024
Generation of four induced pluripotent stem cell lines (KEIUi004-A, KEIUi005-A, KEIUi006-A, and KEIUi007-A) from patients with sensorineural hearing loss with mutation in EYA4 gene.
Journal: Stem cell research
Published: March 18, 2024
Brain-Specific Angiogenesis Inhibitor 3 Is Expressed in the Cochlea and Is Necessary for Hearing Function in Mice.
Journal: International journal of molecular sciences
Published: November 13, 2023
Generation of two induced pluripotent stem cell lines from individuals without auditory disorders.
Journal: Stem cell research
Published: December 04, 2022
Apoptosis of type I spiral ganglion neuron cells in Otof-mutant mice.
Journal: Neuroscience letters
Published: November 29, 2022
Critical roles of FGF, RA, and WNT signalling in the development of the human otic placode and subsequent lineages in a dish.
Journal: Regenerative therapy
Published: March 02, 2022
Deficiency of large tumor suppressor kinase 1 causes congenital hearing loss associated with cochlear abnormalities in mice.
Journal: Biochemical and biophysical research communications
Published: September 28, 2020
Low-dose rapamycin-induced autophagy in cochlear outer sulcus cells.
Journal: Laryngoscope investigative otolaryngology
Published: December 17, 2019
Generation of a human iPS cell line (CGMH.SLC26A4919-2) from a Pendred syndrome patient carrying SLC26A4 c.919-2A>G splice-site mutation.
Journal: Stem cell research
Published: December 17, 2018
Estimating the concentration of therapeutic range using disease-specific iPS cells: Low-dose rapamycin therapy for Pendred syndrome.
Journal: Regenerative therapy
Published: August 10, 2018
Engraftment of Human Pluripotent Stem Cell-derived Progenitors in the Inner Ear of Prenatal Mice.
Journal: Scientific reports
Published: October 03, 2017
Last Updated: 09/26/2026