Chimed W. Jansen
Chemistry, R&D, Oss 5349
Oss, NB, Netherlands
Oss, NB, Netherlands
Last Updated: 09/26/2026
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Found 22 publications
Structure-Guided Optimization of Novel Inhibitors of Plasmodium Lysyl-tRNA Synthetase with Multistage Activity against Malaria Parasites.
Journal: Journal of medicinal chemistry
Published: June 02, 2026
Optimization and Chemoproteomic Profiling of a Selective, Covalent Bfl-1-Targeting Cellular Tool.
Journal: Journal of medicinal chemistry
Published: December 23, 2025
Design and Development of Lysyl tRNA Synthetase Inhibitors, for the Treatment of Tuberculosis.
Journal: Journal of medicinal chemistry
Published: August 01, 2025
Structure-Based Discovery of a Series of Covalent, Orally Bioavailable, and Selective BFL1 Inhibitors.
Journal: Journal of medicinal chemistry
Published: December 06, 2024
Cryptosporidium lysyl-tRNA synthetase inhibitors define the interplay between solubility and permeability required to achieve efficacy.
Journal: Science translational medicine
Published: October 23, 2024
Lysyl-tRNA synthetase, a target for urgently needed M. tuberculosis drugs.
Journal: Nature communications
Published: April 12, 2022
How often and to what extent do admitted COVID-19 patients have signs of cardiac injury?
Journal: Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation
Published: March 31, 2021
Four guidelines on cardiovascular complications and cardiovascular disease, prognosis and treatment in COVID‑19.
Journal: Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation
Published: March 31, 2021
Effect of anticoagulant therapy in COVID-19 patients.
Journal: Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation
Published: March 31, 2021
Impact of cardiovascular disease and cardiovascular risk factors in hospitalised COVID-19 patients.
Journal: Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation
Published: March 31, 2021
Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis.
Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: March 22, 2019
Targeting a Subpocket in Trypanosoma brucei Phosphodiesterase B1 (TbrPDEB1) Enables the Structure-Based Discovery of Selective Inhibitors with Trypanocidal Activity.
Journal: Journal of medicinal chemistry
Published: April 20, 2018
Last Updated: 09/26/2026