Chinh C. Ngo

Canberra, ACT, Australia

Last Updated: 09/26/2026

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Found 21 publications

Pharmacological targeting of the NLRP3 LRR domain with isothiazolinones overcomes CRID3-resistant inflammation.

Pharmacological targeting of the NLRP3 LRR domain with isothiazolinones overcomes CRID3-resistant inflammation.

Journal: EMBO molecular medicine

Published: November 06, 2025

Molecular mechanisms and regulation of inflammasome activation and signaling: sensing of pathogens and damage molecular patterns.

Molecular mechanisms and regulation of inflammasome activation and signaling: sensing of pathogens and damage molecular patterns.

Journal: Cellular & molecular immunology

Published: August 12, 2025

A potent NLRP3 inhibitor effective against both MCC950-sensitive and -resistant inflammation.

A potent NLRP3 inhibitor effective against both MCC950-sensitive and -resistant inflammation.

Journal: Cell chemical biology

Published: February 07, 2025

Inflammasome protein scaffolds the DNA damage complex during tumor development.

Inflammasome protein scaffolds the DNA damage complex during tumor development.

Journal: Nature immunology

Published: February 26, 2024

Ku70 senses cytosolic DNA and assembles a tumor-suppressive signalosome.

Ku70 senses cytosolic DNA and assembles a tumor-suppressive signalosome.

Journal: Science advances

Published: January 26, 2024

Mouse guanylate-binding proteins of the chromosome 3 cluster do not mediate antiviral activity in vitro or in mouse models of infection.

Mouse guanylate-binding proteins of the chromosome 3 cluster do not mediate antiviral activity in vitro or in mouse models of infection.

Journal: Communications biology

Published: November 09, 2023

Impairing Gasdermin D-mediated pyroptosis is protective against retinal degeneration.

Impairing Gasdermin D-mediated pyroptosis is protective against retinal degeneration.

Journal: Journal of neuroinflammation

Published: August 14, 2023

Profiling the colonic mucosal response to fecal microbiota transplantation identifies a role for GBP5 in colitis in humans and mice.

Profiling the colonic mucosal response to fecal microbiota transplantation identifies a role for GBP5 in colitis in humans and mice.

Journal: Nature communications

Published: July 17, 2023

Immunity against Moraxella catarrhalis requires guanylate-binding proteins and caspase-11-NLRP3 inflammasomes.

Immunity against Moraxella catarrhalis requires guanylate-binding proteins and caspase-11-NLRP3 inflammasomes.

Journal: The EMBO journal

Published: September 08, 2022

Clostridium septicum α-toxin activates the NLRP3 inflammasome by engaging GPI-anchored proteins.

Clostridium septicum α-toxin activates the NLRP3 inflammasome by engaging GPI-anchored proteins.

Journal: Science immunology

Published: May 20, 2022

Clostridium perfringens virulence factors are nonredundant activators of the NLRP3 inflammasome.

Clostridium perfringens virulence factors are nonredundant activators of the NLRP3 inflammasome.

Journal: EMBO reports

Published: January 04, 2022

Predominant Bacterial and Viral Otopathogens Identified Within the Respiratory Tract and Middle Ear of Urban Australian Children Experiencing Otitis Media Are Diversely Distributed.

Predominant Bacterial and Viral Otopathogens Identified Within the Respiratory Tract and Middle Ear of Urban Australian Children Experiencing Otitis Media Are Diversely Distributed.

Journal: Frontiers in cellular and infection microbiology

Published: September 14, 2021

Showing 1-12 of 21

Last Updated: 09/26/2026