Chizuru Akatsu

Tokyo, Japan

Last Updated: 09/26/2026

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Found 13 publications

Neu5Gc-mediated high-affinity interaction is dispensable for CD22 cis-ligands to regulate B cell signaling.

Neu5Gc-mediated high-affinity interaction is dispensable for CD22 cis-ligands to regulate B cell signaling.

Journal: The Journal of biological chemistry

Published: July 05, 2024

CD72 is an inhibitory pattern recognition receptor that recognizes ribosomes and suppresses production of anti-ribosome autoantibody.

CD72 is an inhibitory pattern recognition receptor that recognizes ribosomes and suppresses production of anti-ribosome autoantibody.

Journal: Journal of autoimmunity

Published: January 08, 2024

LAPTM5 mediates immature B cell apoptosis and B cell tolerance by regulating the WWP2-PTEN-AKT pathway.

LAPTM5 mediates immature B cell apoptosis and B cell tolerance by regulating the WWP2-PTEN-AKT pathway.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: August 29, 2022

The inhibitory coreceptor CD22 restores B cell signaling by developmentally regulating Cd45-/- immunodeficient B cells.

The inhibitory coreceptor CD22 restores B cell signaling by developmentally regulating Cd45-/- immunodeficient B cells.

Journal: Science signaling

Published: March 01, 2022

The Protein Tyrosine Phosphatase SHP-1 (PTPN6) but Not CD45 (PTPRC) Is Essential for the Ligand-Mediated Regulation of CD22 in BCR-Ligated B Cells.

The Protein Tyrosine Phosphatase SHP-1 (PTPN6) but Not CD45 (PTPRC) Is Essential for the Ligand-Mediated Regulation of CD22 in BCR-Ligated B Cells.

Journal: Journal of immunology (Baltimore, Md. : 1950)

Published: February 03, 2021

Identification of Siglec Cis-Ligands by Proximity Labeling.

Identification of Siglec Cis-Ligands by Proximity Labeling.

Journal: Methods in molecular biology (Clifton, N.J.)

Published: April 20, 2020

Differential Regulation of Thermodynamic Binding Forces of Levocetirizine and (S)-Cetirizine by Lys191 in Human Histamine H₁ Receptors.

Differential Regulation of Thermodynamic Binding Forces of Levocetirizine and (S)-Cetirizine by Lys191 in Human Histamine H₁ Receptors.

Journal: International journal of molecular sciences

Published: November 30, 2018

CD22-Binding Synthetic Sialosides Regulate B Lymphocyte Proliferation Through CD22 Ligand-Dependent and Independent Pathways, and Enhance Antibody Production in Mice.

CD22-Binding Synthetic Sialosides Regulate B Lymphocyte Proliferation Through CD22 Ligand-Dependent and Independent Pathways, and Enhance Antibody Production in Mice.

Journal: Frontiers in immunology

Published: November 12, 2017

Proximity labeling of cis-ligands of CD22/Siglec-2 reveals stepwise α2,6 sialic acid-dependent and -independent interactions.

Proximity labeling of cis-ligands of CD22/Siglec-2 reveals stepwise α2,6 sialic acid-dependent and -independent interactions.

Journal: Biochemical and biophysical research communications

Published: November 07, 2017

Asp73-dependent and -independent regulation of the affinity of ligands for human histamine H1 receptors by Na.

Asp73-dependent and -independent regulation of the affinity of ligands for human histamine H1 receptors by Na.

Journal: Biochemical pharmacology

Published: November 29, 2016

CD72 negatively regulates B lymphocyte responses to the lupus-related endogenous toll-like receptor 7 ligand Sm/RNP.

CD72 negatively regulates B lymphocyte responses to the lupus-related endogenous toll-like receptor 7 ligand Sm/RNP.

Journal: The Journal of experimental medicine

Published: April 19, 2016

C-terminal of human histamine H1 receptors regulates their agonist-induced clathrin-mediated internalization and G-protein signaling.

C-terminal of human histamine H1 receptors regulates their agonist-induced clathrin-mediated internalization and G-protein signaling.

Journal: Journal of neurochemistry

Published: December 11, 2015

Showing 1-12 of 13

Last Updated: 09/26/2026