Christian A. Seemayer

Basel, BS 4051, Switzerland

Last Updated: 09/26/2026

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Found 16 publications

Structure-Activity Relationship Guided Scaffold Hopping Resulted in the Identification of GLPG4970, a Highly Potent Dual SIK2/SIK3 Inhibitor.

Structure-Activity Relationship Guided Scaffold Hopping Resulted in the Identification of GLPG4970, a Highly Potent Dual SIK2/SIK3 Inhibitor.

Journal: Journal of medicinal chemistry

Published: July 25, 2025

GLPG1205 for idiopathic pulmonary fibrosis: a phase 2 randomised placebo-controlled trial.

GLPG1205 for idiopathic pulmonary fibrosis: a phase 2 randomised placebo-controlled trial.

Journal: The European respiratory journal

Published: March 07, 2022

Macroautophagy in Dendritic Cells Controls the Homeostasis and Stability of Regulatory T Cells.

Macroautophagy in Dendritic Cells Controls the Homeostasis and Stability of Regulatory T Cells.

Journal: Cell reports

Published: May 02, 2018

Self-assembled thermoresponsive nanostructures of hyaluronic acid conjugates for osteoarthritis therapy.

Self-assembled thermoresponsive nanostructures of hyaluronic acid conjugates for osteoarthritis therapy.

Journal: Nanoscale

Published: January 09, 2018

Nanocrystals of a potent p38 MAPK inhibitor embedded in microparticles: Therapeutic effects in inflammatory and mechanistic murine models of osteoarthritis.

Nanocrystals of a potent p38 MAPK inhibitor embedded in microparticles: Therapeutic effects in inflammatory and mechanistic murine models of osteoarthritis.

Journal: Journal of controlled release : official journal of the Controlled Release Society

Published: November 21, 2017

Nanocrystal-Polymer Particles: Extended Delivery Carriers for Osteoarthritis Treatment.

Nanocrystal-Polymer Particles: Extended Delivery Carriers for Osteoarthritis Treatment.

Journal: Small (Weinheim an der Bergstrasse, Germany)

Published: September 08, 2017

Modeling the Effect of the Selective S1P1 Receptor Modulator Ponesimod on Subsets of Blood Lymphocytes.

Modeling the Effect of the Selective S1P1 Receptor Modulator Ponesimod on Subsets of Blood Lymphocytes.

Journal: Pharmaceutical research

Published: October 11, 2016

Deficiency in IL-1 Receptor Type 2 Aggravates K/BxN Serum Transfer-Induced Arthritis in Mice but Has No Impact on Systemic Inflammatory Responses.

Deficiency in IL-1 Receptor Type 2 Aggravates K/BxN Serum Transfer-Induced Arthritis in Mice but Has No Impact on Systemic Inflammatory Responses.

Journal: Journal of immunology (Baltimore, Md. : 1950)

Published: May 18, 2016

Effect of particle size on the biodistribution of nano- and microparticles following intra-articular injection in mice.

Effect of particle size on the biodistribution of nano- and microparticles following intra-articular injection in mice.

Journal: International journal of pharmaceutics

Published: September 06, 2015

Severe neutrophil-dominated inflammation and enhanced myelopoiesis in IL-33-overexpressing CMV/IL33 mice.

Severe neutrophil-dominated inflammation and enhanced myelopoiesis in IL-33-overexpressing CMV/IL33 mice.

Journal: Journal of immunology (Baltimore, Md. : 1950)

Published: December 16, 2014

Intra-articular bioactivity of a p38 MAPK inhibitor and development of an extended-release system.

Intra-articular bioactivity of a p38 MAPK inhibitor and development of an extended-release system.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V

Published: October 14, 2014

Immune-mediated experimental arthritis in IL-33 deficient mice.

Immune-mediated experimental arthritis in IL-33 deficient mice.

Journal: Cytokine

Published: July 09, 2013

Showing 1-12 of 16

Last Updated: 09/26/2026