Christian Fledelius

Diabetes Pharmacology 1, Novo Nordisk Park 1
Malov, 2760, Denmark

Last Updated: 09/26/2026

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Found 24 publications

Correction to: Disrupted hypothalamic transcriptomics and proteomics in a mouse model of type 2 diabetes exposed to recurrent hypoglycaemia.

Correction to: Disrupted hypothalamic transcriptomics and proteomics in a mouse model of type 2 diabetes exposed to recurrent hypoglycaemia.

Journal: Diabetologia

Published: January 11, 2024

Glucose-sensitive insulin with attenuation of hypoglycaemia.

Glucose-sensitive insulin with attenuation of hypoglycaemia.

Journal: Nature

Published: May 01, 2023

Disrupted hypothalamic transcriptomics and proteomics in a mouse model of type 2 diabetes exposed to recurrent hypoglycaemia.

Disrupted hypothalamic transcriptomics and proteomics in a mouse model of type 2 diabetes exposed to recurrent hypoglycaemia.

Journal: Diabetologia

Published: April 18, 2023

Standard procedures for blood withdrawal in conscious male rats induce stress and profoundly affect glucose tolerance and secretion of glucoregulatory hormones.

Standard procedures for blood withdrawal in conscious male rats induce stress and profoundly affect glucose tolerance and secretion of glucoregulatory hormones.

Journal: Molecular metabolism

Published: December 07, 2022

An integrated platform approach enables discovery of potent, selective and ligand-competitive cyclic peptides targeting the GIP receptor.

An integrated platform approach enables discovery of potent, selective and ligand-competitive cyclic peptides targeting the GIP receptor.

Journal: Chemical science

Published: December 07, 2021

Molecular Engineering of Insulin Icodec, the First Acylated Insulin Analog for Once-Weekly Administration in Humans.

Molecular Engineering of Insulin Icodec, the First Acylated Insulin Analog for Once-Weekly Administration in Humans.

Journal: Journal of medicinal chemistry

Published: May 04, 2021

Temporal Development of Dyslipidemia and Nonalcoholic Fatty Liver Disease (NAFLD) in Syrian Hamsters Fed a High-Fat, High-Fructose, High-Cholesterol Diet.

Temporal Development of Dyslipidemia and Nonalcoholic Fatty Liver Disease (NAFLD) in Syrian Hamsters Fed a High-Fat, High-Fructose, High-Cholesterol Diet.

Journal: Nutrients

Published: January 18, 2021

Insulin treatment improves liver histopathology and decreases expression of inflammatory and fibrogenic genes in a hyperglycemic, dyslipidemic hamster model of NAFLD.

Insulin treatment improves liver histopathology and decreases expression of inflammatory and fibrogenic genes in a hyperglycemic, dyslipidemic hamster model of NAFLD.

Journal: Journal of translational medicine

Published: November 24, 2020

Insulin Treatment Attenuates Small Nerve Fiber Damage in Rat Model of Type 2 Diabetes.

Insulin Treatment Attenuates Small Nerve Fiber Damage in Rat Model of Type 2 Diabetes.

Journal: Journal of diabetes research

Published: May 20, 2020

Variation in diagnostic NAFLD/NASH read-outs in paired liver samples from rodent models.

Variation in diagnostic NAFLD/NASH read-outs in paired liver samples from rodent models.

Journal: Journal of pharmacological and toxicological methods

Published: July 10, 2019

Peripherally delivered hepatopreferential insulin analog insulin-406 mimics the hypoglycaemia-sparing effect of portal vein human insulin infusion in dogs.

Peripherally delivered hepatopreferential insulin analog insulin-406 mimics the hypoglycaemia-sparing effect of portal vein human insulin infusion in dogs.

Journal: Diabetes, obesity & metabolism

Published: April 26, 2019

Targeting insulin to the liver corrects defects in glucose metabolism caused by peripheral insulin delivery.

Targeting insulin to the liver corrects defects in glucose metabolism caused by peripheral insulin delivery.

Journal: JCI insight

Published: March 05, 2019

Showing 1-12 of 24

Last Updated: 09/26/2026