Christian H. Freund

Leiden, ZH, Netherlands

Last Updated: 09/26/2026

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Found 52 publications

Generation of a STRAIGHT-IN Dual AAVS1 hiPSC line with orthogonal landing pads for versatile DNA payload integration.

Generation of a STRAIGHT-IN Dual AAVS1 hiPSC line with orthogonal landing pads for versatile DNA payload integration.

Journal: Stem cell research
Published: May 21, 2026

Generation of four human induced pluripotent stem cell lines derived from patients with corticosteroid-associated central serous chorioretinopathy.

Generation of four human induced pluripotent stem cell lines derived from patients with corticosteroid-associated central serous chorioretinopathy.

Journal: Stem cell research
Published: March 03, 2026

Generation of patient-derived and gene-corrected hiPSC lines from Hereditary Hemorrhagic Telangiectasia type 2 patients with ACVRL1 c.1042delG mutation.

Generation of patient-derived and gene-corrected hiPSC lines from Hereditary Hemorrhagic Telangiectasia type 2 patients with ACVRL1 c.1042delG mutation.

Journal: Stem cell research
Published: July 09, 2025

A systematic review and embryological perspective of pluripotent stem cell-derived autonomic postganglionic neuron differentiation for human disease modeling.

A systematic review and embryological perspective of pluripotent stem cell-derived autonomic postganglionic neuron differentiation for human disease modeling.

Journal: eLife
Published: October 01, 2024

Generation of XPA p.Arg228T mutant LUMCi004-A cell line for modeling Xeroderma pigmentosum group A.

Generation of XPA p.Arg228T mutant LUMCi004-A cell line for modeling Xeroderma pigmentosum group A.

Journal: Stem cell research
Published: August 19, 2024

Three-dimensional tissue engineered skeletal muscle modelling facioscapulohumeral muscular dystrophy.

Three-dimensional tissue engineered skeletal muscle modelling facioscapulohumeral muscular dystrophy.

Journal: Brain : a journal of neurology
Published: July 18, 2024

Generation and genetic repair of two human induced pluripotent stem cell lines from patients with Epidermolysis Bullosa simplex associated with a heterozygous mutation in the translation initiation codon of KLHL24.

Generation and genetic repair of two human induced pluripotent stem cell lines from patients with Epidermolysis Bullosa simplex associated with a heterozygous mutation in the translation initiation codon of KLHL24.

Journal: Stem cell research
Published: July 15, 2024

The role of DNA methylation in chondrogenesis of human iPSCs as a stable marker of cartilage quality.

The role of DNA methylation in chondrogenesis of human iPSCs as a stable marker of cartilage quality.

Journal: Clinical epigenetics
Published: March 11, 2024

Validating human induced pluripotent stem cell-specific quality control tests for the release of an intermediate drug product in a Good Manufacturing Practice quality system.

Validating human induced pluripotent stem cell-specific quality control tests for the release of an intermediate drug product in a Good Manufacturing Practice quality system.

Journal: Cytotherapy
Published: January 25, 2024

Good Manufacturing Practice-compliant human induced pluripotent stem cells: from bench to putative clinical products.

Good Manufacturing Practice-compliant human induced pluripotent stem cells: from bench to putative clinical products.

Journal: Cytotherapy
Published: November 07, 2023

Genetic repair of a human induced pluripotent cell line from patient with Dutch-type cerebral amyloid angiopathy.

Genetic repair of a human induced pluripotent cell line from patient with Dutch-type cerebral amyloid angiopathy.

Journal: Stem cell research
Published: July 28, 2023

AAV-mediated gene augmentation therapy of CRB1 patient-derived retinal organoids restores the histological and transcriptional retinal phenotype.

AAV-mediated gene augmentation therapy of CRB1 patient-derived retinal organoids restores the histological and transcriptional retinal phenotype.

Journal: Stem cell reports
Published: June 14, 2023
Showing 1-12 of 52

Last Updated: 09/26/2026