Christian J. Leumann
Bern, BE 3012, Switzerland
Last Updated: 09/26/2026
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Found 37 publications
Cell-penetrating peptide-conjugated, splice-switching oligonucleotides mitigate the phenotype in BTK/Tec double deficient X-linked agammaglobulinemia model.
Journal: RSC chemical biology
Published: December 15, 2024
7',5'-alpha-bicyclo-DNA: new chemistry for oligonucleotide exon splicing modulation therapy.
Journal: Nucleic acids research
Published: December 11, 2020
Enzymatic synthesis of biphenyl-DNA oligonucleotides.
Journal: Bioorganic & medicinal chemistry
Published: January 21, 2020
Compatibility of 5-ethynyl-2'F-ANA UTP with in vitro selection for the generation of base-modified, nuclease resistant aptamers.
Journal: Organic & biomolecular chemistry
Published: August 29, 2019
Lowering Mutant Huntingtin Using Tricyclo-DNA Antisense Oligonucleotides As a Therapeutic Approach for Huntington's Disease.
Journal: Nucleic acid therapeutics
Published: June 12, 2019
Synthesis and Enzymatic Characterization of Sugar-Modified Nucleoside Triphosphate Analogs.
Journal: Methods in molecular biology (Clifton, N.J.)
Published: April 25, 2019
NMR solution structure of tricyclo-DNA containing duplexes: insight into enhanced thermal stability and nuclease resistance.
Journal: Nucleic acids research
Published: December 08, 2018
Synthesis, biophysical properties, and RNase H activity of 6'-difluoro[4.3.0]bicyclo-DNA.
Journal: Beilstein journal of organic chemistry
Published: October 15, 2018
6'-Fluoro[4.3.0]bicyclo nucleic acid: synthesis, biophysical properties and molecular dynamics simulations.
Journal: Beilstein journal of organic chemistry
Published: September 26, 2018
Oxidative stress damages rRNA inside the ribosome and differentially affects the catalytic center.
Journal: Nucleic acids research
Published: September 19, 2017
What Hinders Electron Transfer Dissociation (ETD) of DNA Cations?
Journal: Journal of the American Society for Mass Spectrometry
Published: June 29, 2017
Efficacy and Safety Profile of Tricyclo-DNA Antisense Oligonucleotides in Duchenne Muscular Dystrophy Mouse Model.
Journal: Molecular therapy. Nucleic acids
Published: May 22, 2017
Last Updated: 09/26/2026