Christian Kretzer
Jena, TH, Germany
Last Updated: 09/26/2026
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Found 24 publications
Evaluation of molecular mechanisms of (Z)-3-(pentadec-10'-enyl)-catechol (litreol) and synthetic derivatives as inhibitors of human leukotriene biosynthesis.
Journal: Redox biology
Published: July 21, 2025
Discovery of novel microsomal prostaglandin E2 synthase 1 (mPGES-1) inhibitors by a structurally inspired virtual screening study.
Journal: Journal of molecular graphics & modelling
Published: August 12, 2024
Correction: Encapsulation of the dual FLAP/mPEGS‑1 inhibitor BRP‑187 into acetalated dextran and PLGA nanoparticles improves its cellular bioactivity.
Journal: Journal of nanobiotechnology
Published: February 26, 2024
Machine Learning Uncovers Natural Product Modulators of the 5-Lipoxygenase Pathway and Facilitates the Elucidation of Their Biological Mechanisms.
Journal: ACS chemical biology
Published: December 27, 2023
Cannabidiol acts as molecular switch in innate immune cells to promote the biosynthesis of inflammation-resolving lipid mediators.
Journal: Cell chemical biology
Published: January 30, 2023
Label-Free Characterization of Macrophage Polarization Using Raman Spectroscopy.
Journal: International journal of molecular sciences
Published: November 20, 2022
Identification of 2-Aminoacyl-1,3,4-thiadiazoles as Prostaglandin E2 and Leukotriene Biosynthesis Inhibitors.
Journal: ACS medicinal chemistry letters
Published: July 25, 2022
Rotational constriction of curcuminoids impacts 5-lipoxygenase and mPGES-1 inhibition and evokes a lipid mediator class switch in macrophages.
Journal: Biochemical pharmacology
Published: May 18, 2022
Novel potent benzimidazole-based microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitors derived from BRP-201 that also inhibit leukotriene C4 synthase.
Journal: European journal of medicinal chemistry
Published: November 26, 2021
Shifting the Biosynthesis of Leukotrienes Toward Specialized Pro-Resolving Mediators by the 5-Lipoxygenase-Activating Protein (FLAP) Antagonist BRP-201.
Journal: Journal of inflammation research
Published: October 21, 2021
Last Updated: 09/26/2026