Christian Le Gouill

Montreal, QC H3T1J4, Canada

Last Updated: 09/26/2026

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Found 27 publications

TBXA2R activates ERMs to drive motility, invasion, and metastatic colonization of TNBC cells.

TBXA2R activates ERMs to drive motility, invasion, and metastatic colonization of TNBC cells.

Journal: Life science alliance

Published: December 15, 2025

Sustained Gαs signaling mediated by vasopressin type 2 receptors is ligand dependent but endocytosis and β-arrestin independent.

Sustained Gαs signaling mediated by vasopressin type 2 receptors is ligand dependent but endocytosis and β-arrestin independent.

Journal: Science signaling

Published: March 26, 2025

Conformation- and activation-based BRET sensors differentially report on GPCR-G protein coupling.

Conformation- and activation-based BRET sensors differentially report on GPCR-G protein coupling.

Journal: Science signaling

Published: June 18, 2024

Multiple intramolecular triggers converge to preferential G protein coupling in the CB2R.

Multiple intramolecular triggers converge to preferential G protein coupling in the CB2R.

Journal: Nature communications

Published: February 29, 2024

EGFR signaling and pharmacology in oncology revealed with innovative BRET-based biosensors.

EGFR signaling and pharmacology in oncology revealed with innovative BRET-based biosensors.

Journal: Communications biology

Published: June 05, 2023

GLP-1R signaling neighborhoods associate with the susceptibility to adverse drug reactions of incretin mimetics.

GLP-1R signaling neighborhoods associate with the susceptibility to adverse drug reactions of incretin mimetics.

Journal: Nature communications

Published: January 25, 2023

Structural Elements Directing G Proteins and β-Arrestin Interactions with the Human Melatonin Type 2 Receptor Revealed by Natural Variants.

Structural Elements Directing G Proteins and β-Arrestin Interactions with the Human Melatonin Type 2 Receptor Revealed by Natural Variants.

Journal: ACS pharmacology & translational science

Published: July 18, 2022

Michaelis-Menten Quantification of Ligand Signaling Bias Applied to the Promiscuous Vasopressin V2 Receptor.

Michaelis-Menten Quantification of Ligand Signaling Bias Applied to the Promiscuous Vasopressin V2 Receptor.

Journal: Molecular pharmacology

Published: February 10, 2022

Effector membrane translocation biosensors reveal G protein and βarrestin coupling profiles of 100 therapeutically relevant GPCRs.

Effector membrane translocation biosensors reveal G protein and βarrestin coupling profiles of 100 therapeutically relevant GPCRs.

Journal: eLife

Published: September 21, 2021

Identification of Key Regions Mediating Human Melatonin Type 1 Receptor Functional Selectivity Revealed by Natural Variants.

Identification of Key Regions Mediating Human Melatonin Type 1 Receptor Functional Selectivity Revealed by Natural Variants.

Journal: ACS pharmacology & translational science

Published: June 09, 2021

BRET-based effector membrane translocation assay monitors GPCR-promoted and endocytosis-mediated Gq activation at early endosomes.

BRET-based effector membrane translocation assay monitors GPCR-promoted and endocytosis-mediated Gq activation at early endosomes.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: May 15, 2021

Ackr3-Venus knock-in mouse lights up brain vasculature.

Ackr3-Venus knock-in mouse lights up brain vasculature.

Journal: Molecular brain

Published: April 22, 2021

Showing 1-12 of 27

Last Updated: 09/26/2026