Christian M. Grimm

Mansfield Rd
Oxford, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 181 publications

PLASTID ENVELOPE ION CHANNELS (PEC1/2) link Ca2+ and jasmonic acid signaling in plant cells.

PLASTID ENVELOPE ION CHANNELS (PEC1/2) link Ca2+ and jasmonic acid signaling in plant cells.

Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: August 28, 2026

TPC1-dependent control of endosomal pH and transferrin uptake determines cellular iron status.

TPC1-dependent control of endosomal pH and transferrin uptake determines cellular iron status.

Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: August 05, 2026

Phospholipid-driven conformational switching of HCV NS5A links protein folding to replication membrane remodeling.

Phospholipid-driven conformational switching of HCV NS5A links protein folding to replication membrane remodeling.

Journal: Science advances
Published: April 03, 2026

Regulation of Ferroptosis Sensitivity in Hepatocellular Carcinoma Cells by Lysosomal Ion Channels TPC2 and TRPML1.

Regulation of Ferroptosis Sensitivity in Hepatocellular Carcinoma Cells by Lysosomal Ion Channels TPC2 and TRPML1.

Journal: Antioxidants (Basel, Switzerland)
Published: March 30, 2026

Proton-selective conductance and gating of the lysosomal cation channel TMEM175.

Proton-selective conductance and gating of the lysosomal cation channel TMEM175.

Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: January 14, 2026

The Concise Guide to PHARMACOLOGY 2025/26: Ion channels.

The Concise Guide to PHARMACOLOGY 2025/26: Ion channels.

Journal: British journal of pharmacology
Published: December 29, 2025

Allosteric switching of Ca2+ permeability in the lysosomal ion channel TPC2 underpins biased agonist activation.

Allosteric switching of Ca2+ permeability in the lysosomal ion channel TPC2 underpins biased agonist activation.

Journal: The EMBO journal
Published: November 03, 2025

Inhibition of endolysosomal two-pore channel 2 (TPC2) induces osteoblast differentiation and matrix mineralization while targeting autophagy.

Inhibition of endolysosomal two-pore channel 2 (TPC2) induces osteoblast differentiation and matrix mineralization while targeting autophagy.

Journal: Journal of endocrinological investigation
Published: October 21, 2025

RNA interference to reduce Egr1 expression in rods delays retinal degeneration in a model of retinitis pigmentosa.

RNA interference to reduce Egr1 expression in rods delays retinal degeneration in a model of retinitis pigmentosa.

Journal: Molecular vision
Published: October 03, 2025

Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.

Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.

Journal: Frontiers in immunology
Published: July 17, 2025

TRPML1 suppresses pulmonary fibrosis by limiting collagen and elastin deposition.

TRPML1 suppresses pulmonary fibrosis by limiting collagen and elastin deposition.

Journal: The EMBO journal
Published: July 14, 2025

TRPML2 channel modulation by PI(3,5)P₂ and small-molecule agonists controls endosomal vesicle dynamics.

TRPML2 channel modulation by PI(3,5)P₂ and small-molecule agonists controls endosomal vesicle dynamics.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Published: May 22, 2025
Showing 1-12 of 181

Last Updated: 09/26/2026