Christian Pichlo - Publications

Phenotypic Discovery of Triazolo[1,5-c]quinazolines as a First-In-Class Bone Morphogenetic Protein Amplifier Chemotype.

Journal: Journal of medicinal chemistry

Published: November 08, 2022

A structural basis for the diverse linkage specificities within the ZUFSP deubiquitinase family.

Journal: Nature communications

Published: June 14, 2021

Proteasomal degradation induced by DPP9-mediated processing competes with mitochondrial protein import.

Journal: The EMBO journal

Published: November 01, 2019

Molecular determinants of the mechanism and substrate specificity of Clostridium difficile proline-proline endopeptidase-1.

Journal: The Journal of biological chemistry

Published: April 23, 2019

2-Azo-, 2-diazocine-thiazols and 2-azo-imidazoles as photoswitchable kinase inhibitors: limitations and pitfalls of the photoswitchable inhibitor approach.

Journal: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology

Published: March 30, 2019

Loss of GFAT-1 feedback regulation activates the hexosamine pathway that modulates protein homeostasis.

Journal: Nature communications

Published: March 26, 2019

Design, Synthesis and Biological Evaluation of Isoxazole-Based CK1 Inhibitors Modified with Chiral Pyrrolidine Scaffolds.

Journal: Molecules (Basel, Switzerland)

Published: December 12, 2018

Heterologous expression and characterization of a novel serine protease from Daphnia magna: A possible role in susceptibility to toxic cyanobacteria.

Journal: Aquatic toxicology (Amsterdam, Netherlands)

Published: July 10, 2018

Discovery of Inhibitor of Wnt Production 2 (IWP-2) and Related Compounds As Selective ATP-Competitive Inhibitors of Casein Kinase 1 (CK1) δ/ε.

Journal: Journal of medicinal chemistry

Published: April 10, 2018

Improved protein-crystal identification by using 2,2,2-trichloroethanol as a fluorescence enhancer.

Journal: Acta crystallographica. Section F, Structural biology communications

Published: February 24, 2018

A family of unconventional deubiquitinases with modular chain specificity determinants.

Journal: Nature communications

Published: October 05, 2017

Biallelic CHP1 mutation causes human autosomal recessive ataxia by impairing NHE1 function.

Journal: Neurology. Genetics

Published: August 11, 2017