Christian Renn

Bonn, NW 53121, Germany

Last Updated: 09/26/2026

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Found 13 publications

Design, development and evaluation of a tritium-labeled radiotracer for ecto-5'-nucleotidase (CD73) - A versatile research tool and diagnostic agent for personalized medicine.

Design, development and evaluation of a tritium-labeled radiotracer for ecto-5'-nucleotidase (CD73) - A versatile research tool and diagnostic agent for personalized medicine.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Published: March 15, 2025

Acyclic purine and pyrimidine nucleotide analogs as ecto-5'-nucleotidase (CD73) inhibitors.

Acyclic purine and pyrimidine nucleotide analogs as ecto-5'-nucleotidase (CD73) inhibitors.

Journal: European journal of medicinal chemistry

Published: December 04, 2024

Heparins are potent inhibitors of ectonucleotide pyrophosphatase/phospho-diesterase-1 (NPP1) - a promising target for the immunotherapy of cancer.

Heparins are potent inhibitors of ectonucleotide pyrophosphatase/phospho-diesterase-1 (NPP1) - a promising target for the immunotherapy of cancer.

Journal: Frontiers in immunology

Published: February 24, 2023

Targeting two distinct epitopes on human CD73 with a bispecific antibody improves anticancer activity.

Targeting two distinct epitopes on human CD73 with a bispecific antibody improves anticancer activity.

Journal: Journal for immunotherapy of cancer

Published: July 28, 2022

Sulfated Polysaccharides from Macroalgae Are Potent Dual Inhibitors of Human ATP-Hydrolyzing Ectonucleotidases NPP1 and CD39.

Sulfated Polysaccharides from Macroalgae Are Potent Dual Inhibitors of Human ATP-Hydrolyzing Ectonucleotidases NPP1 and CD39.

Journal: Marine drugs

Published: December 29, 2020

Fluorescent Probes for Ecto-5'-nucleotidase (CD73).

Fluorescent Probes for Ecto-5'-nucleotidase (CD73).

Journal: ACS medicinal chemistry letters

Published: July 13, 2020

2-Substituted α,β-Methylene-ADP Derivatives: Potent Competitive Ecto-5'-nucleotidase (CD73) Inhibitors with Variable Binding Modes.

2-Substituted α,β-Methylene-ADP Derivatives: Potent Competitive Ecto-5'-nucleotidase (CD73) Inhibitors with Variable Binding Modes.

Journal: Journal of medicinal chemistry

Published: February 12, 2020

Adenine-(methoxy)-ethoxy-Pα,α-dithio-triphosphate inhibits pathologic calcium pyrophosphate deposition in osteoarthritic human chondrocytes.

Adenine-(methoxy)-ethoxy-Pα,α-dithio-triphosphate inhibits pathologic calcium pyrophosphate deposition in osteoarthritic human chondrocytes.

Journal: Organic & biomolecular chemistry

Published: November 14, 2019

Structure-Activity Relationship of Purine and Pyrimidine Nucleotides as Ecto-5'-Nucleotidase (CD73) Inhibitors.

Structure-Activity Relationship of Purine and Pyrimidine Nucleotides as Ecto-5'-Nucleotidase (CD73) Inhibitors.

Journal: Journal of medicinal chemistry

Published: March 22, 2019

Identification of adenine-N9-(methoxy)ethyl-β-bisphosphonate as NPP1 inhibitor attenuates NPPase activity in human osteoarthritic chondrocytes.

Identification of adenine-N9-(methoxy)ethyl-β-bisphosphonate as NPP1 inhibitor attenuates NPPase activity in human osteoarthritic chondrocytes.

Journal: Purinergic signalling

Published: November 20, 2018

From Type I to Type II: Design, Synthesis, and Characterization of Potent Pyrazin-2-ones as DFG-Out Inhibitors of PDGFRβ.

From Type I to Type II: Design, Synthesis, and Characterization of Potent Pyrazin-2-ones as DFG-Out Inhibitors of PDGFRβ.

Journal: ChemMedChem

Published: September 28, 2016

Pharmacology of novel small-molecule tubulin inhibitors in glioblastoma cells with enhanced EGFR signalling.

Pharmacology of novel small-molecule tubulin inhibitors in glioblastoma cells with enhanced EGFR signalling.

Journal: Biochemical pharmacology

Published: September 09, 2015

Showing 1-12 of 13

Last Updated: 09/26/2026