Christina L. Chai

16 Medical Drive
117600, Singapore

Last Updated: 09/26/2026

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Found 49 publications

Evaluating Molecular Docking Programs for RNA-Targeted Ligand Screening: Influence of Binding Modes and Ligand Types.

Evaluating Molecular Docking Programs for RNA-Targeted Ligand Screening: Influence of Binding Modes and Ligand Types.

Journal: Journal of chemical information and modeling

Published: May 12, 2026

The futility of the familiar: rethinking strategies for the development of small molecules for neurodegenerative disorders.

The futility of the familiar: rethinking strategies for the development of small molecules for neurodegenerative disorders.

Journal: Expert opinion on drug discovery

Published: March 16, 2026

Mutagenesis-Guided Target Identification Reveals the Protein-Binding Domain of Nsp14 in Coronaviruses as the Target of a Labdane-Oxindole Compound.

Mutagenesis-Guided Target Identification Reveals the Protein-Binding Domain of Nsp14 in Coronaviruses as the Target of a Labdane-Oxindole Compound.

Journal: ACS infectious diseases

Published: April 10, 2025

Letting Go of Pains and Other Dogmas.

Letting Go of Pains and Other Dogmas.

Journal: ChemMedChem

Published: March 12, 2025

Privileged natural product compound classes for anti-inflammatory drug development.

Privileged natural product compound classes for anti-inflammatory drug development.

Journal: Natural product reports

Published: March 11, 2025

Calcaratarin D, a labdane diterpenoid, attenuates bleomycin-induced pulmonary fibrosis by blocking Wnt/β-catenin signaling pathway.

Calcaratarin D, a labdane diterpenoid, attenuates bleomycin-induced pulmonary fibrosis by blocking Wnt/β-catenin signaling pathway.

Journal: Pharmacological research

Published: March 04, 2025

Identification of Small-Molecule Inhibitors for Enterovirus A71 IRES by Structure-Based Virtual Screening.

Identification of Small-Molecule Inhibitors for Enterovirus A71 IRES by Structure-Based Virtual Screening.

Journal: Journal of chemical information and modeling

Published: March 01, 2025

Degradation of MK2 with natural compound andrographolide: A new modality for anti-inflammatory therapy.

Degradation of MK2 with natural compound andrographolide: A new modality for anti-inflammatory therapy.

Journal: Pharmacological research

Published: May 05, 2023

Calcaratarin D, a labdane diterpenoid, attenuates mouse asthma via modulating alveolar macrophage function.

Calcaratarin D, a labdane diterpenoid, attenuates mouse asthma via modulating alveolar macrophage function.

Journal: British journal of pharmacology

Published: June 26, 2022

Small-molecule enhancers of CRISPR-induced homology-directed repair in gene therapy: A medicinal chemist's perspective.

Small-molecule enhancers of CRISPR-induced homology-directed repair in gene therapy: A medicinal chemist's perspective.

Journal: Drug discovery today

Published: February 21, 2022

COVID-19 and the promise of small molecule therapeutics: Are there lessons to be learnt?

COVID-19 and the promise of small molecule therapeutics: Are there lessons to be learnt?

Journal: Pharmacological research

Published: February 08, 2022

Discovery and development of labdane-oxindole hybrids as small-molecule inhibitors against chikungunya virus infection.

Discovery and development of labdane-oxindole hybrids as small-molecule inhibitors against chikungunya virus infection.

Journal: European journal of medicinal chemistry

Published: December 01, 2021

Showing 1-12 of 49

Last Updated: 09/26/2026