Christina P. Yap
London, ENG SM25NG, United Kingdom
Last Updated: 09/26/2026
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Found 103 publications
PRO-ADD: Patient-empowered dose-finding trials integrating safety, preliminary efficacy and patient-reported outcomes for optimal dose selection.
Journal: Statistical methods in medical research
Published: April 30, 2026
A Phase I trial of the anti-IL23 monoclonal antibody tildrakizumab, in combination with abiraterone acetate, for the treatment of metastatic castration-resistant prostate cancer.
Journal: Investigational new drugs
Published: February 04, 2026
International Consensus-Driven Recommendations for Patient-Reported Outcome Research Objectives in Early Phase Dose-Finding Oncology Trials: OPTIMISE-ROR.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Published: January 23, 2026
Optimising patient centred drug development to realise impact.
Journal: Communications medicine
Published: January 06, 2026
DOSET: dose optimization with simultaneous efficacy and toxicity evaluation, motivated by a first-in-human phase I CAR T lymphoma trial.
Journal: ESMO open
Published: December 11, 2025
Generalized Pairwise Comparisons in Dose Optimization Oncology Trials: Beyond Safety to Multi-outcome Dose Selection.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research
Published: December 08, 2025
Innovative oncology trial designs: Time to act - A review with recommendations of the Cancer Drug Development Forum.
Journal: Journal of cancer policy
Published: December 02, 2025
Phase I Trial of Ipatasertib plus Atezolizumab Enhances PI3K/AKT Pathway Immune Responses in Solid Tumors and Refractory Glioblastoma.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research
Published: November 24, 2025
A practical toolkit with recommendations for analysing and visualising patient-reported outcomes in early phase dose-finding oncology trials (OPTIMISE-AR).
Journal: The Lancet. Oncology
Published: October 26, 2025
Expansion cohorts in phase 1 oncology trials: a systematic review of their design, implementation and outcomes.
Journal: British journal of cancer
Published: July 27, 2025
Response adaptive randomisation in clinical trials: Current practice, gaps and future directions.
Journal: Statistical methods in medical research
Published: June 18, 2025
Clinical Trial Simulation: Planning With the OCTAVE Framework, Implementation and Validation Principles.
Journal: Statistics in medicine
Published: February 21, 2025
Last Updated: 09/26/2026