Christine Thumann

Strasbourg, 67000, France

Last Updated: 09/26/2026

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Found 17 publications

Claudin-1 targeting suppresses tumor growth, invasion, and metastasis in patient-derived cholangiocarcinoma models.

Claudin-1 targeting suppresses tumor growth, invasion, and metastasis in patient-derived cholangiocarcinoma models.

Journal: Science translational medicine
Published: June 03, 2026

A monoclonal antibody targeting nonjunctional claudin-1 inhibits fibrosis in patient-derived models by modulating cell plasticity.

A monoclonal antibody targeting nonjunctional claudin-1 inhibits fibrosis in patient-derived models by modulating cell plasticity.

Journal: Science translational medicine
Published: December 21, 2022

Treatment of HCC with claudin-1-specific antibodies suppresses carcinogenic signaling and reprograms the tumor microenvironment.

Treatment of HCC with claudin-1-specific antibodies suppresses carcinogenic signaling and reprograms the tumor microenvironment.

Journal: Journal of hepatology
Published: February 21, 2022

A human liver cell-based system modeling a clinical prognostic liver signature for therapeutic discovery.

A human liver cell-based system modeling a clinical prognostic liver signature for therapeutic discovery.

Journal: Nature communications
Published: July 16, 2020

Targeting clinical epigenetic reprogramming for chemoprevention of metabolic and viral hepatocellular carcinoma.

Targeting clinical epigenetic reprogramming for chemoprevention of metabolic and viral hepatocellular carcinoma.

Journal: Gut
Published: April 17, 2019

HCV-Induced Epigenetic Changes Associated With Liver Cancer Risk Persist After Sustained Virologic Response.

HCV-Induced Epigenetic Changes Associated With Liver Cancer Risk Persist After Sustained Virologic Response.

Journal: Gastroenterology
Published: December 10, 2018

Humanisation of a claudin-1-specific monoclonal antibody for clinical prevention and cure of HCV infection without escape.

Humanisation of a claudin-1-specific monoclonal antibody for clinical prevention and cure of HCV infection without escape.

Journal: Gut
Published: July 05, 2016

Solute Carrier NTCP Regulates Innate Antiviral Immune Responses Targeting Hepatitis C Virus Infection of Hepatocytes.

Solute Carrier NTCP Regulates Innate Antiviral Immune Responses Targeting Hepatitis C Virus Infection of Hepatocytes.

Journal: Cell reports
Published: April 18, 2016

Hepatitis C Virus-Induced Upregulation of MicroRNA miR-146a-5p in Hepatocytes Promotes Viral Infection and Deregulates Metabolic Pathways Associated with Liver Disease Pathogenesis.

Hepatitis C Virus-Induced Upregulation of MicroRNA miR-146a-5p in Hepatocytes Promotes Viral Infection and Deregulates Metabolic Pathways Associated with Liver Disease Pathogenesis.

Journal: Journal of virology
Published: April 01, 2016

Clearance of persistent hepatitis C virus infection in humanized mice using a claudin-1-targeting monoclonal antibody.

Clearance of persistent hepatitis C virus infection in humanized mice using a claudin-1-targeting monoclonal antibody.

Journal: Nature biotechnology
Published: October 01, 2014

Synergy of entry inhibitors with direct-acting antivirals uncovers novel combinations for prevention and treatment of hepatitis C.

Synergy of entry inhibitors with direct-acting antivirals uncovers novel combinations for prevention and treatment of hepatitis C.

Journal: Gut
Published: May 23, 2014

Exosome-mediated transmission of hepatitis C virus between human hepatoma Huh7.5 cells.

Exosome-mediated transmission of hepatitis C virus between human hepatoma Huh7.5 cells.

Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: July 24, 2013
Showing 1-12 of 17

Last Updated: 09/26/2026