Christoph Fischli

Basel, BS, Switzerland

Last Updated: 09/26/2026

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Found 12 publications

Translation of liver stage activity of M5717, a Plasmodium elongation factor 2 inhibitor: from bench to bedside.

Translation of liver stage activity of M5717, a Plasmodium elongation factor 2 inhibitor: from bench to bedside.

Journal: Malaria journal

Published: December 03, 2021

3-Hydroxy-propanamidines, a New Class of Orally Active Antimalarials Targeting Plasmodium falciparum.

3-Hydroxy-propanamidines, a New Class of Orally Active Antimalarials Targeting Plasmodium falciparum.

Journal: Journal of medicinal chemistry

Published: March 05, 2021

Flexible 3D Cell-Based Platforms for the Discovery and Profiling of Novel Drugs Targeting Plasmodium Hepatic Infection.

Flexible 3D Cell-Based Platforms for the Discovery and Profiling of Novel Drugs Targeting Plasmodium Hepatic Infection.

Journal: ACS infectious diseases

Published: September 04, 2019

Antimalarial pantothenamide metabolites target acetyl-coenzyme A biosynthesis in Plasmodium falciparum.

Antimalarial pantothenamide metabolites target acetyl-coenzyme A biosynthesis in Plasmodium falciparum.

Journal: Science translational medicine

Published: January 12, 2018

3-Hydroxy-N'-arylidenepropanehydrazonamides with Halo-Substituted Phenanthrene Scaffolds Cure P. berghei Infected Mice When Administered Perorally.

3-Hydroxy-N'-arylidenepropanehydrazonamides with Halo-Substituted Phenanthrene Scaffolds Cure P. berghei Infected Mice When Administered Perorally.

Journal: Journal of medicinal chemistry

Published: June 28, 2017

Discovery and Characterization of ACT-451840: an Antimalarial Drug with a Novel Mechanism of Action.

Discovery and Characterization of ACT-451840: an Antimalarial Drug with a Novel Mechanism of Action.

Journal: ChemMedChem

Published: June 13, 2016

Characterization of Novel Antimalarial Compound ACT-451840: Preclinical Assessment of Activity and Dose-Efficacy Modeling.

Characterization of Novel Antimalarial Compound ACT-451840: Preclinical Assessment of Activity and Dose-Efficacy Modeling.

Journal: PLoS medicine

Published: October 14, 2015

Pharmacokinetic-pharmacodynamic analysis of spiroindolone analogs and KAE609 in a murine malaria model.

Pharmacokinetic-pharmacodynamic analysis of spiroindolone analogs and KAE609 in a murine malaria model.

Journal: Antimicrobial agents and chemotherapy

Published: December 10, 2014

Targeting Plasmodium PI(4)K to eliminate malaria.

Targeting Plasmodium PI(4)K to eliminate malaria.

Journal: Nature

Published: July 23, 2013

Novel in vivo active anti-malarials based on a hydroxy-ethyl-amine scaffold.

Novel in vivo active anti-malarials based on a hydroxy-ethyl-amine scaffold.

Journal: Bioorganic & medicinal chemistry letters

Published: October 23, 2012

Identification of a new chemical class of antimalarials.

Identification of a new chemical class of antimalarials.

Journal: The Journal of infectious diseases

Published: June 27, 2012

Imidazolopiperazines: lead optimization of the second-generation antimalarial agents.

Imidazolopiperazines: lead optimization of the second-generation antimalarial agents.

Journal: Journal of medicinal chemistry

Published: April 25, 2012

Showing 1-12 of 12

Last Updated: 09/26/2026