Christoph Schachtele

ProQinase GmbH, Breisacher Str. 117
Freiburg, BW 79106, Germany

Last Updated: 09/26/2026

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Found 22 publications

Novel SAR for quinazoline inhibitors of EHMT1 and EHMT2.

Novel SAR for quinazoline inhibitors of EHMT1 and EHMT2.

Journal: Bioorganic & medicinal chemistry letters

Published: December 23, 2018

Mouse-Derived Isograft (MDI) In Vivo Tumor Models II. Carcinogen-Induced cMDI Models: Characterization and Cancer Therapeutic Approaches.

Mouse-Derived Isograft (MDI) In Vivo Tumor Models II. Carcinogen-Induced cMDI Models: Characterization and Cancer Therapeutic Approaches.

Journal: Cancers

Published: December 01, 2018

Mouse-Derived Isograft (MDI) In Vivo Tumor Models I. Spontaneous sMDI Models: Characterization and Cancer Therapeutic Approaches.

Mouse-Derived Isograft (MDI) In Vivo Tumor Models I. Spontaneous sMDI Models: Characterization and Cancer Therapeutic Approaches.

Journal: Cancers

Published: December 01, 2018

Hydrophobic Derivatives of Glycopeptide Antibiotics as Inhibitors of Protein Kinases.

Hydrophobic Derivatives of Glycopeptide Antibiotics as Inhibitors of Protein Kinases.

Journal: Biochemistry. Biokhimiia

Published: November 27, 2018

Novel Protein Kinase Inhibitors Related to Tau Pathology Modulate Tau Protein-Self Interaction Using a Luciferase Complementation Assay.

Novel Protein Kinase Inhibitors Related to Tau Pathology Modulate Tau Protein-Self Interaction Using a Luciferase Complementation Assay.

Journal: Molecules (Basel, Switzerland)

Published: June 27, 2018

Discovery of novel dual inhibitors of receptor tyrosine kinases EGFR and PDGFR-β related to anticancer drug resistance.

Discovery of novel dual inhibitors of receptor tyrosine kinases EGFR and PDGFR-β related to anticancer drug resistance.

Journal: Journal of enzyme inhibition and medicinal chemistry

Published: November 04, 2017

Discovery of novel dual inhibitors of receptor tyrosine kinases EGFR and IGF-1R.

Discovery of novel dual inhibitors of receptor tyrosine kinases EGFR and IGF-1R.

Journal: Journal of enzyme inhibition and medicinal chemistry

Published: January 18, 2017

Scaffold hopping identifies 6,8-disubstituted purines as novel anaplastic lymphoma kinase inhibitors.

Scaffold hopping identifies 6,8-disubstituted purines as novel anaplastic lymphoma kinase inhibitors.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V

Published: January 11, 2017

Discovery of novel substituted benzo-anellated 4-benzylamino pyrrolopyrimidines as dual EGFR and VEGFR2 inhibitors.

Discovery of novel substituted benzo-anellated 4-benzylamino pyrrolopyrimidines as dual EGFR and VEGFR2 inhibitors.

Journal: Bioorganic & medicinal chemistry letters

Published: November 18, 2016

Drug Development of Small-Molecule Inhibitors of AD-Relevant Kinases as Novel Perspective Multitargeted Approach.

Drug Development of Small-Molecule Inhibitors of AD-Relevant Kinases as Novel Perspective Multitargeted Approach.

Journal: Current Alzheimer research

Published: January 25, 2016

Cell lines expressing recombinant transmembrane domain-activated receptor kinases as tools for drug discovery.

Cell lines expressing recombinant transmembrane domain-activated receptor kinases as tools for drug discovery.

Journal: Journal of biomolecular screening

Published: September 28, 2014

Optimization of potent DFG-in inhibitors of platelet derived growth factor receptorβ (PDGF-Rβ) guided by water thermodynamics.

Optimization of potent DFG-in inhibitors of platelet derived growth factor receptorβ (PDGF-Rβ) guided by water thermodynamics.

Journal: Journal of medicinal chemistry

Published: July 10, 2014

Showing 1-12 of 22

Last Updated: 09/26/2026