Christophe A. Goncalves

Montreal, QC H3T1E2, Canada

Last Updated: 09/26/2026

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Found 39 publications

Hepatic inflammation after exposure to a mixture of low-dose arsenic and cadmium in a murine model of fatty liver disease.

Hepatic inflammation after exposure to a mixture of low-dose arsenic and cadmium in a murine model of fatty liver disease.

Journal: Toxicological sciences : an official journal of the Society of Toxicology

Published: June 12, 2026

Corrigendum to 'The Role of eIF4E in Response and Acquired Resistance to Vemurafenib in Melanoma': [Journal of Investigative Dermatology, Volume 135, Issue 5, May 2015, Pages 1368-1376].

Corrigendum to 'The Role of eIF4E in Response and Acquired Resistance to Vemurafenib in Melanoma': [Journal of Investigative Dermatology, Volume 135, Issue 5, May 2015, Pages 1368-1376].

Journal: The Journal of investigative dermatology

Published: March 13, 2026

mTOR inhibition enhances the antitumor efficacy of pan-RAF-MEK blockade by inhibiting the ATF4-MTHFD2 pathway.

mTOR inhibition enhances the antitumor efficacy of pan-RAF-MEK blockade by inhibiting the ATF4-MTHFD2 pathway.

Journal: Cell death & disease

Published: November 10, 2025

Protocol for antibody optimization and panel design in high-dimensional multiplexed immunofluorescence imaging.

Protocol for antibody optimization and panel design in high-dimensional multiplexed immunofluorescence imaging.

Journal: STAR protocols

Published: September 12, 2025

The CCL17-CCR4 Axis Is Critical for Mutant STAT6-Mediated Microenvironmental Remodeling and Therapeutic Resistance in Relapsed/Refractory Diffuse Large B-Cell Lymphoma.

The CCL17-CCR4 Axis Is Critical for Mutant STAT6-Mediated Microenvironmental Remodeling and Therapeutic Resistance in Relapsed/Refractory Diffuse Large B-Cell Lymphoma.

Journal: Cancer immunology research

Published: May 07, 2025

Lack of phospho-eIF4E worsens experimental colitis by inhibiting Treg suppressive activity.

Lack of phospho-eIF4E worsens experimental colitis by inhibiting Treg suppressive activity.

Journal: Journal of inflammation (London, England)

Published: April 28, 2025

RAB1A is a novel vulnerability in uveal melanoma revealed by dual inhibition of MNK1/2 and mTOR.

RAB1A is a novel vulnerability in uveal melanoma revealed by dual inhibition of MNK1/2 and mTOR.

Journal: Cell death and differentiation

Published: April 16, 2025

Blocking tumor-intrinsic MNK1 kinase restricts metabolic adaptation and diminishes liver metastasis.

Blocking tumor-intrinsic MNK1 kinase restricts metabolic adaptation and diminishes liver metastasis.

Journal: Science advances

Published: September 13, 2024

Inhibiting the MNK1/2-eIF4E axis impairs melanoma phenotype switching and potentiates antitumor immune responses.

Inhibiting the MNK1/2-eIF4E axis impairs melanoma phenotype switching and potentiates antitumor immune responses.

Journal: The Journal of clinical investigation

Published: May 01, 2024

Correction: MNK1/NODAL Signaling Promotes Invasive Progression of Breast Ductal Carcinoma In Situ.

Correction: MNK1/NODAL Signaling Promotes Invasive Progression of Breast Ductal Carcinoma In Situ.

Journal: Cancer research

Published: April 15, 2024

MNK1/2 inhibition limits oncogenicity and metastasis of KIT-mutant melanoma.

MNK1/2 inhibition limits oncogenicity and metastasis of KIT-mutant melanoma.

Journal: The Journal of clinical investigation

Published: April 15, 2024

Phase Ib Pharmacodynamic Study of the MNK Inhibitor Tomivosertib (eFT508) Combined With Paclitaxel in Patients With Refractory Metastatic Breast Cancer.

Phase Ib Pharmacodynamic Study of the MNK Inhibitor Tomivosertib (eFT508) Combined With Paclitaxel in Patients With Refractory Metastatic Breast Cancer.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research

Published: March 22, 2024

Showing 1-12 of 39

Last Updated: 09/26/2026