Christophe Broca

Montpellier, France

Last Updated: 09/26/2026

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Found 16 publications

Simultaneous kidney-islet transplantation from a donor after circulatory death using normothermic regional perfusion.

Simultaneous kidney-islet transplantation from a donor after circulatory death using normothermic regional perfusion.

Journal: Transplant international : official journal of the European Society for Organ Transplantation

Published: April 22, 2026

GLP-1 and GIP receptors signal through distinct β-arrestin 2-dependent pathways to regulate pancreatic β cell function.

GLP-1 and GIP receptors signal through distinct β-arrestin 2-dependent pathways to regulate pancreatic β cell function.

Journal: Cell reports

Published: May 10, 2023

Pharmacological activation of insulin-degrading enzyme improves insulin secretion and glucose tolerance in diet-induced obese mice.

Pharmacological activation of insulin-degrading enzyme improves insulin secretion and glucose tolerance in diet-induced obese mice.

Journal: Diabetes, obesity & metabolism

Published: March 05, 2023

Prolonged culture of human pancreatic islets under glucotoxic conditions changes their acute beta cell calcium and insulin secretion glucose response curves from sigmoid to bell-shaped.

Prolonged culture of human pancreatic islets under glucotoxic conditions changes their acute beta cell calcium and insulin secretion glucose response curves from sigmoid to bell-shaped.

Journal: Diabetologia

Published: June 09, 2022

Direct reprogramming of human fibroblasts into insulin-producing cells using transcription factors.

Direct reprogramming of human fibroblasts into insulin-producing cells using transcription factors.

Journal: Communications biology

Published: December 03, 2021

The nuclear receptor REV-ERBα is implicated in the alteration of β-cell autophagy and survival under diabetogenic conditions.

The nuclear receptor REV-ERBα is implicated in the alteration of β-cell autophagy and survival under diabetogenic conditions.

Journal: Cell death & disease

Published: July 05, 2021

SGLT2 is not expressed in pancreatic α- and β-cells, and its inhibition does not directly affect glucagon and insulin secretion in rodents and humans.

SGLT2 is not expressed in pancreatic α- and β-cells, and its inhibition does not directly affect glucagon and insulin secretion in rodents and humans.

Journal: Molecular metabolism

Published: July 30, 2020

Differential sensitivity of human islets from obese versus lean donors to chronic high glucose or palmitate.

Differential sensitivity of human islets from obese versus lean donors to chronic high glucose or palmitate.

Journal: Journal of diabetes

Published: July 09, 2019

PSMB10, the last immunoproteasome gene missing for PRAAS.

PSMB10, the last immunoproteasome gene missing for PRAAS.

Journal: The Journal of allergy and clinical immunology

Published: May 20, 2019

Wisp1 is a circulating factor that stimulates proliferation of adult mouse and human beta cells.

Wisp1 is a circulating factor that stimulates proliferation of adult mouse and human beta cells.

Journal: Nature communications

Published: February 13, 2019

Targeting pancreatic islet PTP1B improves islet graft revascularization and transplant outcomes.

Targeting pancreatic islet PTP1B improves islet graft revascularization and transplant outcomes.

Journal: Science translational medicine

Published: December 15, 2017

Proteasomal degradation of the histone acetyl transferase p300 contributes to beta-cell injury in a diabetes environment.

Proteasomal degradation of the histone acetyl transferase p300 contributes to beta-cell injury in a diabetes environment.

Journal: Cell death & disease

Published: October 18, 2017

Showing 1-12 of 16

Last Updated: 09/26/2026