Christophe Dardonville

Madrid, MD 28006, Spain

Last Updated: 09/26/2026

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Found 41 publications

Immunochemotherapy with Amphotericin B and HisAK70 Vaccine for Cutaneous Leishmaniosis.

Immunochemotherapy with Amphotericin B and HisAK70 Vaccine for Cutaneous Leishmaniosis.

Journal: International journal of molecular sciences

Published: May 28, 2026

Kinetoplast-Directed Therapies: A Selective Mitochondrial Approach to Combat Leishmaniasis.

Kinetoplast-Directed Therapies: A Selective Mitochondrial Approach to Combat Leishmaniasis.

Journal: Pharmaceuticals (Basel, Switzerland)

Published: February 22, 2026

Direct amidinium-phosphate interactions guide AT-selective DNA binding by a potent antileishmanial drug.

Direct amidinium-phosphate interactions guide AT-selective DNA binding by a potent antileishmanial drug.

Journal: Communications chemistry

Published: November 24, 2025

Discovery and SAR studies of antiviral 4-aminopiperidine derivatives active against SARS-CoV-2.

Discovery and SAR studies of antiviral 4-aminopiperidine derivatives active against SARS-CoV-2.

Journal: European journal of medicinal chemistry

Published: September 25, 2025

Development of self-emulsifying drug delivery systems (SEDDS) to improve the bioavailability of a new antileishmanial drug.

Development of self-emulsifying drug delivery systems (SEDDS) to improve the bioavailability of a new antileishmanial drug.

Journal: International journal of pharmaceutics

Published: September 11, 2025

Uncovering the Unusual Inhibition Mechanism of a Trypanosome Alternative Oxidase Inhibitor Displaying Broad-Spectrum Activity against African Animal Trypanosomes.

Uncovering the Unusual Inhibition Mechanism of a Trypanosome Alternative Oxidase Inhibitor Displaying Broad-Spectrum Activity against African Animal Trypanosomes.

Journal: Journal of medicinal chemistry

Published: June 04, 2025

Development and Characterization of a New Oral Antileishmanial Bis(pyridine-2-Carboxamidine) Drug Through Innovative Dissolution Testing in Biorelevant Media Combined with Pharmacokinetic Studies.

Development and Characterization of a New Oral Antileishmanial Bis(pyridine-2-Carboxamidine) Drug Through Innovative Dissolution Testing in Biorelevant Media Combined with Pharmacokinetic Studies.

Journal: Pharmaceutics

Published: May 13, 2025

Crystal structure of the HMGA AT-hook 1 domain bound to the minor groove of AT-rich DNA and inhibition by antikinetoplastid drugs.

Crystal structure of the HMGA AT-hook 1 domain bound to the minor groove of AT-rich DNA and inhibition by antikinetoplastid drugs.

Journal: Scientific reports

Published: August 23, 2024

Synthesis and Biophysical and Biological Studies of N-Phenylbenzamide Derivatives Targeting Kinetoplastid Parasites.

Synthesis and Biophysical and Biological Studies of N-Phenylbenzamide Derivatives Targeting Kinetoplastid Parasites.

Journal: Journal of medicinal chemistry

Published: September 20, 2023

Methyl N-(tert-butoxycarbonyl)pyridine-2-carbimidothioate: A new reagent for the synthesis of N-phenylpyridinecarboxamidine ("arylimidamide") DNA-minor groove binders from poorly nucleophilic amines.

Methyl N-(tert-butoxycarbonyl)pyridine-2-carbimidothioate: A new reagent for the synthesis of N-phenylpyridinecarboxamidine ("arylimidamide") DNA-minor groove binders from poorly nucleophilic amines.

Journal: Bioorganic & medicinal chemistry letters

Published: June 28, 2022

Imidazoline- and Benzamidine-Based Trypanosome Alternative Oxidase Inhibitors: Synthesis and Structure-Activity Relationship Studies.

Imidazoline- and Benzamidine-Based Trypanosome Alternative Oxidase Inhibitors: Synthesis and Structure-Activity Relationship Studies.

Journal: ACS medicinal chemistry letters

Published: December 22, 2021

Synthesis, biological, and photophysical studies of molecular rotor-based fluorescent inhibitors of the trypanosome alternative oxidase.

Synthesis, biological, and photophysical studies of molecular rotor-based fluorescent inhibitors of the trypanosome alternative oxidase.

Journal: European journal of medicinal chemistry

Published: February 01, 2021

Showing 1-12 of 41

Last Updated: 09/26/2026