Christophe Romier

Illkirch-graffenstaden, 67400, France

Last Updated: 09/26/2026

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Found 64 publications

Benzodeazaoxaflavin Sirtuin Inhibitors Inhibit Schistosoma mansoni Sirt2 and Cause Phenotypic Changes and Lethality in Schistosomula and Adult Worm Stages.

Benzodeazaoxaflavin Sirtuin Inhibitors Inhibit Schistosoma mansoni Sirt2 and Cause Phenotypic Changes and Lethality in Schistosomula and Adult Worm Stages.

Journal: ACS infectious diseases
Published: October 07, 2025

Disrupted transcriptional networks regulated by CHD1L during neurodevelopment underlie the mirrored neuroanatomical and growth phenotypes of the 1q21.1 copy number variant.

Disrupted transcriptional networks regulated by CHD1L during neurodevelopment underlie the mirrored neuroanatomical and growth phenotypes of the 1q21.1 copy number variant.

Journal: Nucleic acids research
Published: January 15, 2025

ADAT3 variants disrupt the activity of the ADAT tRNA deaminase complex and impair neuronal migration.

ADAT3 variants disrupt the activity of the ADAT tRNA deaminase complex and impair neuronal migration.

Journal: Brain : a journal of neurology
Published: November 06, 2024

Structure-Activity Studies of 1,2,4-Oxadiazoles for the Inhibition of the NAD+-Dependent Lysine Deacylase Sirtuin 2.

Structure-Activity Studies of 1,2,4-Oxadiazoles for the Inhibition of the NAD+-Dependent Lysine Deacylase Sirtuin 2.

Journal: Journal of medicinal chemistry
Published: June 07, 2024

The cohesin ATPase cycle is mediated by specific conformational dynamics and interface plasticity of SMC1A and SMC3 ATPase domains.

The cohesin ATPase cycle is mediated by specific conformational dynamics and interface plasticity of SMC1A and SMC3 ATPase domains.

Journal: Cell reports
Published: December 15, 2023

Development of First-in-Class Dual Sirt2/HDAC6 Inhibitors as Molecular Tools for Dual Inhibition of Tubulin Deacetylation.

Development of First-in-Class Dual Sirt2/HDAC6 Inhibitors as Molecular Tools for Dual Inhibition of Tubulin Deacetylation.

Journal: Journal of medicinal chemistry
Published: October 30, 2023

Development of Alkylated Hydrazides as Highly Potent and Selective Class I Histone Deacetylase Inhibitors with T cell Modulatory Properties.

Development of Alkylated Hydrazides as Highly Potent and Selective Class I Histone Deacetylase Inhibitors with T cell Modulatory Properties.

Journal: Journal of medicinal chemistry
Published: November 30, 2022

Synthesis, Biochemical, and Cellular Evaluation of HDAC6 Targeting Proteolysis Targeting Chimeras.

Synthesis, Biochemical, and Cellular Evaluation of HDAC6 Targeting Proteolysis Targeting Chimeras.

Journal: Methods in molecular biology (Clifton, N.J.)
Published: October 18, 2022

Chemically Diverse S. mansoni HDAC8 Inhibitors Reduce Viability in Worm Larval and Adult Stages.

Chemically Diverse S. mansoni HDAC8 Inhibitors Reduce Viability in Worm Larval and Adult Stages.

Journal: ChemMedChem
Published: September 21, 2022

In cellulo and in vivo assays for compound testing against Trypanosoma cruzi.

In cellulo and in vivo assays for compound testing against Trypanosoma cruzi.

Journal: STAR protocols
Published: August 16, 2022

Design, Synthesis and Biological Characterization of Histone Deacetylase 8 (HDAC8) Proteolysis Targeting Chimeras (PROTACs) with Anti-Neuroblastoma Activity.

Design, Synthesis and Biological Characterization of Histone Deacetylase 8 (HDAC8) Proteolysis Targeting Chimeras (PROTACs) with Anti-Neuroblastoma Activity.

Journal: International journal of molecular sciences
Published: May 24, 2022

Efficient CRISPR-Cas9-mediated genome editing for characterization of essential genes in Trypanosoma cruzi.

Efficient CRISPR-Cas9-mediated genome editing for characterization of essential genes in Trypanosoma cruzi.

Journal: STAR protocols
Published: May 02, 2022
Showing 1-12 of 64

Last Updated: 09/26/2026