Christopher A. Lewis

Copenhagen, Denmark

Last Updated: 09/26/2026

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Found 19 publications

Myosin ATPase Inhibition Relieves the Energetic Burden in Skeletal Myofibres of Patients With Heart Failure With Reduced Ejection Fraction.

Myosin ATPase Inhibition Relieves the Energetic Burden in Skeletal Myofibres of Patients With Heart Failure With Reduced Ejection Fraction.

Journal: Circulation. Heart failure

Published: May 06, 2026

Impaired Cardiac Myosin Super-Relaxation as an Energy-Dissipating Process in Human Heart Failure with Reduced Ejection Fraction.

Impaired Cardiac Myosin Super-Relaxation as an Energy-Dissipating Process in Human Heart Failure with Reduced Ejection Fraction.

Journal: JACC. Basic to translational science

Published: April 22, 2026

Semaglutide mitigates the loss of fat-free mass and decreased energy expenditure observed after diet restriction. Insights from an obese minipig model.

Semaglutide mitigates the loss of fat-free mass and decreased energy expenditure observed after diet restriction. Insights from an obese minipig model.

Journal: American journal of physiology. Endocrinology and metabolism

Published: February 11, 2026

Semaglutide mitigates the loss of fat-free mass and decreased energy expenditure observed after diet restriction. Insights from an obese minipig model.

Semaglutide mitigates the loss of fat-free mass and decreased energy expenditure observed after diet restriction. Insights from an obese minipig model.

Journal: American journal of physiology. Endocrinology and metabolism

Published: February 11, 2026

Changes in cardiac myosin acetylation disrupt the super-relaxed state in genotype-negative hypertrophic cardiomyopathy with type 2 diabetes.

Changes in cardiac myosin acetylation disrupt the super-relaxed state in genotype-negative hypertrophic cardiomyopathy with type 2 diabetes.

Journal: Cardiovascular diabetology

Published: January 29, 2026

Destabilization of cardiac myosin acetylation and sequestration with type 2 diabetes mellitus.

Destabilization of cardiac myosin acetylation and sequestration with type 2 diabetes mellitus.

Journal: Cardiovascular diabetology

Published: September 29, 2025

Heterogeneous Dysregulation of Myosin Super-Relaxation and Energetics in Hypertrophic Cardiomyopathy.

Heterogeneous Dysregulation of Myosin Super-Relaxation and Energetics in Hypertrophic Cardiomyopathy.

Journal: Circulation. Heart failure

Published: May 20, 2025

Site-specific quantification of the in vivo UFMylome reveals myosin modification in ALS.

Site-specific quantification of the in vivo UFMylome reveals myosin modification in ALS.

Journal: Cell reports methods

Published: December 09, 2024

Pathogenic TNNT1 variants are associated with aberrant thin filament compliance and myofibre hyper-contractility.

Pathogenic TNNT1 variants are associated with aberrant thin filament compliance and myofibre hyper-contractility.

Journal: The Journal of physiology

Published: November 13, 2024

Increased cardiac myosin super-relaxation as an energy saving mechanism in hibernating grizzly bears.

Increased cardiac myosin super-relaxation as an energy saving mechanism in hibernating grizzly bears.

Journal: Molecular metabolism

Published: October 24, 2024

Dysregulated skeletal muscle myosin super-relaxation and energetics in male participants with type 2 diabetes mellitus.

Dysregulated skeletal muscle myosin super-relaxation and energetics in male participants with type 2 diabetes mellitus.

Journal: Diabetologia

Published: October 11, 2024

Super-relaxed myosins contribute to respiratory muscle hibernation in mechanically ventilated patients.

Super-relaxed myosins contribute to respiratory muscle hibernation in mechanically ventilated patients.

Journal: Science translational medicine

Published: July 31, 2024

Showing 1-12 of 19

Last Updated: 09/26/2026