Christopher D. Lloyd

Oncology R&D
Cambridge, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 14 publications

Employing deep mutational scanning in the Escherichia coli periplasm to decode the thermodynamic landscape for amyloid formation.

Employing deep mutational scanning in the Escherichia coli periplasm to decode the thermodynamic landscape for amyloid formation.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: September 17, 2025

Pulmonary Hypertension Promotes Neuroinflammation and Neurodegeneration.

Pulmonary Hypertension Promotes Neuroinflammation and Neurodegeneration.

Journal: bioRxiv : the preprint server for biology

Published: September 15, 2025

An affinity-modulated T cell engager targeting Claudin 18.2 shows potent anti-tumor activity with limited cytokine release.

An affinity-modulated T cell engager targeting Claudin 18.2 shows potent anti-tumor activity with limited cytokine release.

Journal: Journal for immunotherapy of cancer

Published: July 07, 2025

Inpp5d haplodeficiency alleviates tau pathology in the PS19 mouse model of Tauopathy.

Inpp5d haplodeficiency alleviates tau pathology in the PS19 mouse model of Tauopathy.

Journal: Alzheimer's & dementia : the journal of the Alzheimer's Association

Published: April 08, 2024

MEDI1814 selectively reduces free Aβ42 in cerebrospinal fluid of non-clinical species and Alzheimer's disease patients.

MEDI1814 selectively reduces free Aβ42 in cerebrospinal fluid of non-clinical species and Alzheimer's disease patients.

Journal: Alzheimer's & dementia : the journal of the Alzheimer's Association

Published: April 03, 2024

Characterizing Molecular and Synaptic Signatures in mouse models of Late-Onset Alzheimer's Disease Independent of Amyloid and Tau Pathology.

Characterizing Molecular and Synaptic Signatures in mouse models of Late-Onset Alzheimer's Disease Independent of Amyloid and Tau Pathology.

Journal: bioRxiv : the preprint server for biology

Published: January 08, 2024

Characterizing molecular and synaptic signatures in mouse models of late-onset Alzheimer's disease independent of amyloid and tau pathology.

Characterizing molecular and synaptic signatures in mouse models of late-onset Alzheimer's disease independent of amyloid and tau pathology.

Journal: Alzheimer's & dementia : the journal of the Alzheimer's Association

Published: December 13, 2023

Plcg2M28L Interacts With High Fat/High Sugar Diet to Accelerate Alzheimer's Disease-Relevant Phenotypes in Mice.

Plcg2M28L Interacts With High Fat/High Sugar Diet to Accelerate Alzheimer's Disease-Relevant Phenotypes in Mice.

Journal: Frontiers in aging neuroscience

Published: February 28, 2022

Impact of CTLA-4 checkpoint antibodies on ligand binding and Transendocytosis.

Impact of CTLA-4 checkpoint antibodies on ligand binding and Transendocytosis.

Journal: Frontiers in immunology

Published: February 08, 2022

An in vivo platform to select and evolve aggregation-resistant proteins.

An in vivo platform to select and evolve aggregation-resistant proteins.

Journal: Nature communications

Published: November 11, 2019

Preclinical development of a high affinity α-synuclein antibody, MEDI1341, that can enter the brain, sequester extracellular α-synuclein and attenuate α-synuclein spreading in vivo.

Preclinical development of a high affinity α-synuclein antibody, MEDI1341, that can enter the brain, sequester extracellular α-synuclein and attenuate α-synuclein spreading in vivo.

Journal: Neurobiology of disease

Published: July 19, 2019

Preclinical Evaluation of MEDI0641, a Pyrrolobenzodiazepine-Conjugated Antibody-Drug Conjugate Targeting 5T4.

Preclinical Evaluation of MEDI0641, a Pyrrolobenzodiazepine-Conjugated Antibody-Drug Conjugate Targeting 5T4.

Journal: Molecular cancer therapeutics

Published: December 01, 2016

Showing 1-12 of 14

Last Updated: 09/26/2026