Christopher D. Huston

Infectious Disease

111 Colchester Ave
Burlington, VT 05401

Last Updated: 09/26/2026

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Found 53 publications

Identification of UCB-9721 as a potent inhibitor of MyoA, the essential class XIV myosin motor of apicomplexan parasites.

Identification of UCB-9721 as a potent inhibitor of MyoA, the essential class XIV myosin motor of apicomplexan parasites.

Journal: bioRxiv : the preprint server for biology

Published: June 29, 2026

Identification of UCB-9721 as a potent inhibitor of MyoA, the essential class XIV myosin motor of apicomplexan parasites.

Identification of UCB-9721 as a potent inhibitor of MyoA, the essential class XIV myosin motor of apicomplexan parasites.

Journal: bioRxiv : the preprint server for biology

Published: June 29, 2026

Structure-Activity Relationship Study of Anti-Cryptosporidium Benzoxaboroles Yields Enhanced Potency and Curative Efficacy.

Structure-Activity Relationship Study of Anti-Cryptosporidium Benzoxaboroles Yields Enhanced Potency and Curative Efficacy.

Journal: Journal of medicinal chemistry

Published: May 29, 2026

Randomized clinical trial evaluating triazolopyridazine SLU-2633 as a treatment for gastric cryptosporidiosis in eastern indigo snakes (Drymarchon couperi).

Randomized clinical trial evaluating triazolopyridazine SLU-2633 as a treatment for gastric cryptosporidiosis in eastern indigo snakes (Drymarchon couperi).

Journal: Parasitology international

Published: February 09, 2026

Development of a current Good Manufacturing Practice-compliant Process for Producing Cryptosporidium parvum oocysts for Clinical Use.

Development of a current Good Manufacturing Practice-compliant Process for Producing Cryptosporidium parvum oocysts for Clinical Use.

Journal: The Journal of infectious diseases

Published: October 18, 2025

Organoid-based in vitro system and reporter for the study of Cryptosporidium parvum sexual reproduction.

Organoid-based in vitro system and reporter for the study of Cryptosporidium parvum sexual reproduction.

Journal: Microbiology spectrum

Published: June 25, 2025

A propidium iodide-based in vitro screen of the "Bug Box" against Babesia duncani reveals potent inhibitors.

A propidium iodide-based in vitro screen of the "Bug Box" against Babesia duncani reveals potent inhibitors.

Journal: Antimicrobial agents and chemotherapy

Published: June 09, 2025

Synthesis of β-fluoropyrrolidines designed to reduce hERG affinity in a class of antiparasitic compounds.

Synthesis of β-fluoropyrrolidines designed to reduce hERG affinity in a class of antiparasitic compounds.

Journal: ChemistrySelect

Published: March 11, 2025

Discovery of an Orally Efficacious Pyrazolo[3,4-d]pyrimidine Benzoxaborole as a Potent Inhibitor of Cryptosporidium.

Discovery of an Orally Efficacious Pyrazolo[3,4-d]pyrimidine Benzoxaborole as a Potent Inhibitor of Cryptosporidium.

Journal: Journal of medicinal chemistry

Published: December 23, 2024

Cryptosporidium lysyl-tRNA synthetase inhibitors define the interplay between solubility and permeability required to achieve efficacy.

Cryptosporidium lysyl-tRNA synthetase inhibitors define the interplay between solubility and permeability required to achieve efficacy.

Journal: Science translational medicine

Published: October 23, 2024

Cryptosporidium life cycle small molecule probing implicates translational repression and an Apetala 2 transcription factor in macrogamont differentiation.

Cryptosporidium life cycle small molecule probing implicates translational repression and an Apetala 2 transcription factor in macrogamont differentiation.

Journal: PLoS pathogens

Published: December 15, 2023

Organoid-based in vitro system and reporter for the study of Cryptosporidium parvum sexual reproduction.

Organoid-based in vitro system and reporter for the study of Cryptosporidium parvum sexual reproduction.

Journal: bioRxiv : the preprint server for biology

Published: October 09, 2023

Showing 1-12 of 53

Last Updated: 09/26/2026