Christopher J. Farady
Basel, BS 4002, Switzerland
Last Updated: 09/26/2026
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Found 24 publications
Discovery of NP3-742: A Structurally Diverse NLRP3 Inhibitor Identified through an Unusual Phenol Replacement.
Journal: Journal of medicinal chemistry
Published: October 15, 2025
Accurate and reliable detection of clonal hematopoiesis in plasma cell-free DNA.
Journal: Blood advances
Published: May 30, 2025
Discovery of NP3-253, a Potent Brain Penetrant Inhibitor of the NLRP3 Inflammasome.
Journal: Journal of medicinal chemistry
Published: November 22, 2024
A cereblon-based glue degrader of NEK7 regulates NLRP3 inflammasome in a context-dependent manner.
Journal: Cell chemical biology
Published: November 12, 2024
Clonal Hematopoiesis of Indeterminate Potential With Loss of Tet2 Enhances Risk for Atrial Fibrillation Through Nlrp3 Inflammasome Activation.
Journal: Circulation
Published: February 15, 2024
Discovery of Potent, Orally Bioavailable, Tricyclic NLRP3 Inhibitors.
Journal: Journal of medicinal chemistry
Published: January 04, 2024
HDAC6/aggresome processing pathway importance for inflammasome formation is context dependent.
Journal: bioRxiv : the preprint server for biology
Published: August 30, 2023
HDAC6/aggresome processing pathway importance for inflammasome formation is context-dependent.
Journal: The Journal of biological chemistry
Published: August 21, 2023
Crystal Structure of NLRP3 NACHT Domain With an Inhibitor Defines Mechanism of Inflammasome Inhibition.
Journal: Journal of molecular biology
Published: August 13, 2021
Last Updated: 09/26/2026