Christopher J. Lupton

Clayton, VIC, Australia

Last Updated: 09/26/2026

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Found 15 publications

Structural basis for independent pore function of Vpb4 from Bacillus thuringiensis.

Structural basis for independent pore function of Vpb4 from Bacillus thuringiensis.

Journal: Nature communications

Published: August 07, 2025

Structure of the lysosomal KICSTOR-GATOR1-SAMTOR nutrient-sensing supercomplex.

Structure of the lysosomal KICSTOR-GATOR1-SAMTOR nutrient-sensing supercomplex.

Journal: Cell

Published: April 15, 2025

Inhibiting heme piracy by pathogenic Escherichia coli using de novo-designed proteins.

Inhibiting heme piracy by pathogenic Escherichia coli using de novo-designed proteins.

Journal: Nature communications

Published: January 17, 2025

Structure of the human TSC:WIPI3 lysosomal recruitment complex.

Structure of the human TSC:WIPI3 lysosomal recruitment complex.

Journal: Science advances

Published: November 20, 2024

Acidic pH can attenuate immune killing through inactivation of perforin.

Acidic pH can attenuate immune killing through inactivation of perforin.

Journal: EMBO reports

Published: July 07, 2024

LYCHOS is a human hybrid of a plant-like PIN transporter and a GPCR.

LYCHOS is a human hybrid of a plant-like PIN transporter and a GPCR.

Journal: Nature

Published: September 18, 2023

The neoepitope of the complement C5b-9 Membrane Attack Complex is formed by proximity of adjacent ancillary regions of C9.

The neoepitope of the complement C5b-9 Membrane Attack Complex is formed by proximity of adjacent ancillary regions of C9.

Journal: Communications biology

Published: July 04, 2022

Helical ultrastructure of the metalloprotease meprin α in complex with a small molecule inhibitor.

Helical ultrastructure of the metalloprotease meprin α in complex with a small molecule inhibitor.

Journal: Nature communications

Published: March 13, 2022

Thermoresponsive chiral plasmonic nanoparticles.

Thermoresponsive chiral plasmonic nanoparticles.

Journal: Nanoscale

Published: March 04, 2022

Structure of the metastatic factor P-Rex1 reveals a two-layered autoinhibitory mechanism.

Structure of the metastatic factor P-Rex1 reveals a two-layered autoinhibitory mechanism.

Journal: Nature structural & molecular biology

Published: January 17, 2022

Structural analysis of the PTEN:P-Rex2 signaling complex reveals how cancer-associated mutations coordinate to hyperactivate Rac1.

Structural analysis of the PTEN:P-Rex2 signaling complex reveals how cancer-associated mutations coordinate to hyperactivate Rac1.

Journal: Science signaling

Published: May 05, 2021

The cryo-EM structure of the human neurofibromin dimer reveals the molecular basis for neurofibromatosis type 1.

The cryo-EM structure of the human neurofibromin dimer reveals the molecular basis for neurofibromatosis type 1.

Journal: Nature structural & molecular biology

Published: April 20, 2021

Showing 1-12 of 15

Last Updated: 09/26/2026