Christopher L. Millington
Oxford, ENG, United Kingdom
Last Updated: 09/26/2026
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Found 17 publications
Metabolite-induced DNA damage drives stochastic stem cell loss and clonal hematopoiesis.
Journal: Cell stem cell
Published: May 02, 2025
DNA polymerase kappa is the primary translesion synthesis polymerase for aldehyde ICLs.
Journal: Nucleic acids research
Published: March 31, 2025
A tumour-derived organoid biobank maps cancer gene dependencies.
Journal: Nature
Published: February 06, 2025
Iron deficiency causes aspartate-sensitive dysfunction in CD8+ T cells.
Journal: Nature communications
Published: January 29, 2024
Aldehyde-mediated inhibition of asparagine biosynthesis has implications for diabetes and alcoholism.
Journal: Chemical science
Published: December 06, 2023
Formaldehyde regulates S-adenosylmethionine biosynthesis and one-carbon metabolism.
Journal: Science (New York, N.Y.)
Published: November 02, 2023
Aldehyde-driven transcriptional stress triggers an anorexic DNA damage response.
Journal: Nature
Published: June 16, 2020
CDK activity provides temporal and quantitative cues for organizing genome duplication.
Journal: PLoS genetics
Published: August 14, 2017
Bypass of Mutagenic O(6)-Carboxymethylguanine DNA Adducts by Human Y- and B-Family Polymerases.
Journal: Chemical research in toxicology
Published: July 13, 2016
O⁶-carboxymethylguanine in DNA forms a sequence context-dependent wobble base-pair structure with thymine.
Journal: Acta crystallographica. Section D, Biological crystallography
Published: January 24, 2014
Structures of DNA duplexes containing O6-carboxymethylguanine, a lesion associated with gastrointestinal cancer, reveal a mechanism for inducing pyrimidine transition mutations.
Journal: Nucleic acids research
Published: April 13, 2013
Last Updated: 09/26/2026