Christopher N. Foley

Edinburgh, SCT EH89BT, United Kingdom

Last Updated: 09/26/2026

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Found 42 publications

Elevated DYRK1A in Primary Tauopathies and Therapeutic Targeting with the Brain-Penetrant Inhibitor DYR533.

Elevated DYRK1A in Primary Tauopathies and Therapeutic Targeting with the Brain-Penetrant Inhibitor DYR533.

Journal: Research square

Published: September 03, 2026

Dyrk1a inhibition with the Novel Compound DYR533: A Cross-Disease Therapeutic Strategy Targeting Amyloidosis, Tau Pathogenesis, and Neuroinflammation.

Dyrk1a inhibition with the Novel Compound DYR533: A Cross-Disease Therapeutic Strategy Targeting Amyloidosis, Tau Pathogenesis, and Neuroinflammation.

Journal: bioRxiv : the preprint server for biology

Published: February 06, 2026

Proteomic prediction of disease largely reflects environmental risk exposure.

Proteomic prediction of disease largely reflects environmental risk exposure.

Journal: medRxiv : the preprint server for health sciences

Published: September 05, 2025

Discovery and Functional Characterization of a Potent, Selective, and Metabolically Stable PROTAC of the Protein Kinases DYRK1A and DYRK1B.

Discovery and Functional Characterization of a Potent, Selective, and Metabolically Stable PROTAC of the Protein Kinases DYRK1A and DYRK1B.

Journal: Journal of medicinal chemistry

Published: September 30, 2024

Association of Vascular Risk Factors and Cerebrovascular Pathology With Alzheimer Disease Pathologic Changes in Individuals Without Dementia.

Association of Vascular Risk Factors and Cerebrovascular Pathology With Alzheimer Disease Pathologic Changes in Individuals Without Dementia.

Journal: Neurology

Published: September 17, 2024

Editorial: Methods in applied genetic epidemiology 2022.

Editorial: Methods in applied genetic epidemiology 2022.

Journal: Frontiers in genetics

Published: July 23, 2024

Systematic discovery of gene-environment interactions underlying the human plasma proteome in UK Biobank.

Systematic discovery of gene-environment interactions underlying the human plasma proteome in UK Biobank.

Journal: Nature communications

Published: March 07, 2024

Alzheimer's disease genetic pathways impact cerebrospinal fluid biomarkers and imaging endophenotypes in non-demented individuals.

Alzheimer's disease genetic pathways impact cerebrospinal fluid biomarkers and imaging endophenotypes in non-demented individuals.

Journal: Alzheimer's & dementia : the journal of the Alzheimer's Association

Published: October 31, 2023

Author Correction: FinnGen provides genetic insights from a well-phenotyped isolated population.

Author Correction: FinnGen provides genetic insights from a well-phenotyped isolated population.

Journal: Nature

Published: February 24, 2023

Genetic map of regional sulcal morphology in the human brain from UK biobank data.

Genetic map of regional sulcal morphology in the human brain from UK biobank data.

Journal: Nature communications

Published: March 10, 2022

FinnGen provides genetic insights from a well-phenotyped isolated population.

FinnGen provides genetic insights from a well-phenotyped isolated population.

Journal: Nature

Published: January 10, 2022

DYRK1A antagonists rescue degeneration and behavioural deficits of in vivo models based on amyloid-β, Tau and DYRK1A neurotoxicity.

DYRK1A antagonists rescue degeneration and behavioural deficits of in vivo models based on amyloid-β, Tau and DYRK1A neurotoxicity.

Journal: Scientific reports

Published: November 09, 2021

Showing 1-12 of 42

Last Updated: 09/26/2026