Christopher R. Bye

Melbourne, VIC, Australia

Last Updated: 09/26/2026

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Found 14 publications

Large-scale drug screening in iPSC-derived motor neurons from sporadic ALS patients identifies a potential combinatorial therapy.

Large-scale drug screening in iPSC-derived motor neurons from sporadic ALS patients identifies a potential combinatorial therapy.

Journal: Nature neuroscience
Published: May 25, 2023

α-Amino-3-hydroxyl-5-methyl-4-isoxazole-propionate receptor and RNA processing gene dysregulation are early determinants of selective motor neuron vulnerability in a mouse model of amyotrophic lateral sclerosis.

α-Amino-3-hydroxyl-5-methyl-4-isoxazole-propionate receptor and RNA processing gene dysregulation are early determinants of selective motor neuron vulnerability in a mouse model of amyotrophic lateral sclerosis.

Journal: Brain communications
Published: December 08, 2020

TDP-43 Triggers Mitochondrial DNA Release via mPTP to Activate cGAS/STING in ALS.

TDP-43 Triggers Mitochondrial DNA Release via mPTP to Activate cGAS/STING in ALS.

Journal: Cell
Published: January 26, 2020

Viral Delivery of GDNF Promotes Functional Integration of Human Stem Cell Grafts in Parkinson's Disease.

Viral Delivery of GDNF Promotes Functional Integration of Human Stem Cell Grafts in Parkinson's Disease.

Journal: Cell stem cell
Published: May 20, 2019

Transcriptional Profiling of Xenogeneic Transplants: Examining Human Pluripotent Stem Cell-Derived Grafts in the Rodent Brain.

Transcriptional Profiling of Xenogeneic Transplants: Examining Human Pluripotent Stem Cell-Derived Grafts in the Rodent Brain.

Journal: Stem cell reports
Published: April 17, 2019

Axonal Growth of Midbrain Dopamine Neurons is Modulated by the Cell Adhesion Molecule ALCAM Through Trans-Heterophilic Interactions with L1cam, Chl1, and Semaphorins.

Axonal Growth of Midbrain Dopamine Neurons is Modulated by the Cell Adhesion Molecule ALCAM Through Trans-Heterophilic Interactions with L1cam, Chl1, and Semaphorins.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience
Published: February 05, 2019

Association of Regulatory T-Cell Expansion With Progression of Amyotrophic Lateral Sclerosis: A Study of Humans and a Transgenic Mouse Model.

Association of Regulatory T-Cell Expansion With Progression of Amyotrophic Lateral Sclerosis: A Study of Humans and a Transgenic Mouse Model.

Journal: JAMA neurology
Published: March 07, 2018

Specification of murine ground state pluripotent stem cells to regional neuronal populations.

Specification of murine ground state pluripotent stem cells to regional neuronal populations.

Journal: Scientific reports
Published: June 21, 2017

Role of Dopamine 2 Receptor in Impaired Drug-Cue Extinction in Adolescent Rats.

Role of Dopamine 2 Receptor in Impaired Drug-Cue Extinction in Adolescent Rats.

Journal: Cerebral cortex (New York, N.Y. : 1991)
Published: March 07, 2016

Meningeal cells influence midbrain development and the engraftment of dopamine progenitors in Parkinsonian mice.

Meningeal cells influence midbrain development and the engraftment of dopamine progenitors in Parkinsonian mice.

Journal: Experimental neurology
Published: November 17, 2014

Diverse roles for Wnt7a in ventral midbrain neurogenesis and dopaminergic axon morphogenesis.

Diverse roles for Wnt7a in ventral midbrain neurogenesis and dopaminergic axon morphogenesis.

Journal: Stem cells and development
Published: May 08, 2014

Ryk, a receptor regulating Wnt5a-mediated neurogenesis and axon morphogenesis of ventral midbrain dopaminergic neurons.

Ryk, a receptor regulating Wnt5a-mediated neurogenesis and axon morphogenesis of ventral midbrain dopaminergic neurons.

Journal: Stem cells and development
Published: March 23, 2013
Showing 1-12 of 14

Last Updated: 09/26/2026