Christopher Chen

Hematology | Oncology

440 Broadway St
Ste 35
Redwood City, CA 94063

Last Updated: 09/26/2026

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Found 37 publications

Targeting BRAF Class II and III Mutations in NSCLC with the pan-RAF inhibitor Exarafenib Reveals ARAF-KSR1-Mediated Resistance and Rational Combination Strategies.

Targeting BRAF Class II and III Mutations in NSCLC with the pan-RAF inhibitor Exarafenib Reveals ARAF-KSR1-Mediated Resistance and Rational Combination Strategies.

Journal: Research square

Published: November 24, 2025

Pan-RAF inhibitor exarafenib targets BRAF class II/III NSCLC and reveals ARAF-KSR1 resistance and combination strategies.

Pan-RAF inhibitor exarafenib targets BRAF class II/III NSCLC and reveals ARAF-KSR1 resistance and combination strategies.

Journal: Nature communications

Published: October 07, 2025

Durable response to an anti-CD25 antibody-drug conjugate and anti-PD-1 antibody in ovarian carcinoma: a case report.

Durable response to an anti-CD25 antibody-drug conjugate and anti-PD-1 antibody in ovarian carcinoma: a case report.

Journal: Immunotherapy

Published: September 19, 2025

Immunotherapy Efficacy in Mismatch Repair-Proficient Colorectal Cancer Patients With and Without Liver Metastases.

Immunotherapy Efficacy in Mismatch Repair-Proficient Colorectal Cancer Patients With and Without Liver Metastases.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Published: September 11, 2025

Clinical benefit of various HER2-directed regimens in gastrointestinal malignancies: a retrospective cohort study.

Clinical benefit of various HER2-directed regimens in gastrointestinal malignancies: a retrospective cohort study.

Journal: BMC cancer

Published: August 05, 2025

Phase 1 Study of [177Lu]Lu-NeoB in Patients with Advanced Solid Tumors Overexpressing Gastrin-Releasing Peptide Receptor: Preliminary Safety and Dosimetry Results.

Phase 1 Study of [177Lu]Lu-NeoB in Patients with Advanced Solid Tumors Overexpressing Gastrin-Releasing Peptide Receptor: Preliminary Safety and Dosimetry Results.

Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Published: May 30, 2025

p53 Drives Lung Cancer Regression through a TSC2/TFEB-dependent Senescence Program.

p53 Drives Lung Cancer Regression through a TSC2/TFEB-dependent Senescence Program.

Journal: Cancer discovery

Published: March 24, 2025

Milademetan in Advanced Solid Tumors with MDM2 Amplification and Wild-type TP53: Preclinical and Phase II Clinical Trial Results.

Milademetan in Advanced Solid Tumors with MDM2 Amplification and Wild-type TP53: Preclinical and Phase II Clinical Trial Results.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research

Published: March 06, 2025

Phase II trial of organ preservation program using short-course radiation and FOLFOXIRI for rectal cancer (SHORT-FOX): Two-Year primary outcome analysis.

Phase II trial of organ preservation program using short-course radiation and FOLFOXIRI for rectal cancer (SHORT-FOX): Two-Year primary outcome analysis.

Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Published: December 16, 2024

Redefining Available Therapy in Oncology Accelerated Approval Decisions.

Redefining Available Therapy in Oncology Accelerated Approval Decisions.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Published: October 25, 2024

NCCN Guidelines® Insights: Colorectal Cancer Screening, Version 1.2024.

NCCN Guidelines® Insights: Colorectal Cancer Screening, Version 1.2024.

Journal: Journal of the National Comprehensive Cancer Network : JNCCN

Published: September 05, 2024

MDM2 inhibition is associated with the emergence of TP53-altered clonal hematopoiesis.

MDM2 inhibition is associated with the emergence of TP53-altered clonal hematopoiesis.

Journal: NPJ precision oncology

Published: July 15, 2024

Showing 1-12 of 37

Last Updated: 09/26/2026