Chun Wang

Shanghai Key Laboratory Of Signaling And Disease Research
Shanghai, 200092, China

Last Updated: 09/26/2026

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Found 13 publications

TPN10475 alleviates concanavalin A-induced autoimmune hepatitis by limiting T cell development and function through inhibition of PI3K-AKT pathway.

TPN10475 alleviates concanavalin A-induced autoimmune hepatitis by limiting T cell development and function through inhibition of PI3K-AKT pathway.

Journal: International immunopharmacology
Published: August 16, 2023

Manganese Exacerbates ConA-Induced Liver Inflammation via the cGAS-STING Signaling Pathway.

Manganese Exacerbates ConA-Induced Liver Inflammation via the cGAS-STING Signaling Pathway.

Journal: Inflammation
Published: August 09, 2023

TPN10475 Constrains Effector T Lymphocytes Activation and Attenuates Experimental Autoimmune Encephalomyelitis Pathogenesis by Facilitating TGF-β Signal Transduction.

TPN10475 Constrains Effector T Lymphocytes Activation and Attenuates Experimental Autoimmune Encephalomyelitis Pathogenesis by Facilitating TGF-β Signal Transduction.

Journal: Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology
Published: July 21, 2023

The novel small molecule TPN10518 alleviates EAE pathogenesis by inhibiting AP1 to depress Th1/Th17 cell differentiation.

The novel small molecule TPN10518 alleviates EAE pathogenesis by inhibiting AP1 to depress Th1/Th17 cell differentiation.

Journal: International immunopharmacology
Published: May 30, 2023

Purinergic receptor P2Y12 boosts autoimmune hepatitis through hexokinase 2-dependent glycolysis in T cells.

Purinergic receptor P2Y12 boosts autoimmune hepatitis through hexokinase 2-dependent glycolysis in T cells.

Journal: International journal of biological sciences
Published: April 10, 2023

CXCR1 drives the pathogenesis of EAE and ARDS via boosting dendritic cells-dependent inflammation.

CXCR1 drives the pathogenesis of EAE and ARDS via boosting dendritic cells-dependent inflammation.

Journal: Cell death & disease
Published: March 29, 2023

Carboplatin ameliorates the pathogenesis of experimental autoimmune encephalomyelitis by inducing T cell apoptosis.

Carboplatin ameliorates the pathogenesis of experimental autoimmune encephalomyelitis by inducing T cell apoptosis.

Journal: International immunopharmacology
Published: January 24, 2023

Novel evaluation indicators of MOG35∼55 induced experimental autoimmune encephalomyelitis in C57BL/6J mice.

Novel evaluation indicators of MOG35∼55 induced experimental autoimmune encephalomyelitis in C57BL/6J mice.

Journal: Immunobiology
Published: October 04, 2022

Induction and Diverse Assessment Indicators of Experimental Autoimmune Encephalomyelitis.

Induction and Diverse Assessment Indicators of Experimental Autoimmune Encephalomyelitis.

Journal: Journal of visualized experiments : JoVE
Published: September 26, 2022

TPN10466 ameliorates Concanavalin A-induced autoimmune hepatitis in mice via inhibiting ERK/JNK/p38 signaling pathway.

TPN10466 ameliorates Concanavalin A-induced autoimmune hepatitis in mice via inhibiting ERK/JNK/p38 signaling pathway.

Journal: European journal of immunology
Published: July 26, 2022

Artemisinin derivative TPN10466 suppresses immune cell migration and Th1/Th17 differentiation to ameliorate disease severity in experimental autoimmune encephalomyelitis.

Artemisinin derivative TPN10466 suppresses immune cell migration and Th1/Th17 differentiation to ameliorate disease severity in experimental autoimmune encephalomyelitis.

Journal: Cellular immunology
Published: September 28, 2021

Methyl acetate arrests Th1 in peripheral immune system and alleviates CNS inflammation in EAE.

Methyl acetate arrests Th1 in peripheral immune system and alleviates CNS inflammation in EAE.

Journal: International immunopharmacology
Published: August 09, 2021
Showing 1-12 of 13

Last Updated: 09/26/2026