Chunquan J. Sheng

325 Guohe Road
Shanghai, 200433, China

Last Updated: 09/26/2026

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Found 201 publications

Discovery of a Potent NAMPT-Targeting PROTAC for the Suppression of Triple-Negative Breast Cancer via Macrophage Reprogramming.

Discovery of a Potent NAMPT-Targeting PROTAC for the Suppression of Triple-Negative Breast Cancer via Macrophage Reprogramming.

Journal: Journal of medicinal chemistry

Published: July 06, 2026

GID4-Recruiting PROTACs for BRD4 Degradation Overcome Resistance Driven by CRBN and VHL Deficiency.

GID4-Recruiting PROTACs for BRD4 Degradation Overcome Resistance Driven by CRBN and VHL Deficiency.

Journal: Journal of medicinal chemistry

Published: July 05, 2026

Discovery of Novel Hsp90 Inhibitor-Evodiamine Derivative Conjugates as Potent and Orally Active Antitumor Agents for Colon Cancer Therapy.

Discovery of Novel Hsp90 Inhibitor-Evodiamine Derivative Conjugates as Potent and Orally Active Antitumor Agents for Colon Cancer Therapy.

Journal: Journal of medicinal chemistry

Published: May 28, 2026

Discovery of New Pyrazolone Derivatives for Treating Invasive Fungal Infections by Iron Homeostasis Disruption.

Discovery of New Pyrazolone Derivatives for Treating Invasive Fungal Infections by Iron Homeostasis Disruption.

Journal: Journal of medicinal chemistry

Published: May 04, 2026

Discovery of a Nicotinamide Phosphoribosyltransferase (NAMPT) Activator for Improving Muscle Function and Alleviating Fatigue.

Discovery of a Nicotinamide Phosphoribosyltransferase (NAMPT) Activator for Improving Muscle Function and Alleviating Fatigue.

Journal: Journal of medicinal chemistry

Published: April 16, 2026

Dual-targeting evodiamine analogue overcomes pancreatic cancer immunotherapy resistance by inducing immunogenic cell death.

Dual-targeting evodiamine analogue overcomes pancreatic cancer immunotherapy resistance by inducing immunogenic cell death.

Journal: Biochemical pharmacology

Published: February 22, 2026

GSDME/IL-18 pyroptotic axis prevents myosteatosis by expanding tissue-resident macrophages to promote muscle regeneration.

GSDME/IL-18 pyroptotic axis prevents myosteatosis by expanding tissue-resident macrophages to promote muscle regeneration.

Journal: The Journal of clinical investigation

Published: February 17, 2026

Traditional medicine-derived natural products as anti-osteoporotic Agents: A review on structural modifications, mechanisms, and structure-activity relationships.

Traditional medicine-derived natural products as anti-osteoporotic Agents: A review on structural modifications, mechanisms, and structure-activity relationships.

Journal: European journal of medicinal chemistry

Published: January 16, 2026

Strategies for targeted protein degradation through lysosomal pathways.

Strategies for targeted protein degradation through lysosomal pathways.

Journal: Advanced drug delivery reviews

Published: December 09, 2025

Inhibiting Mrt4-rRNA interaction with fumaramidmycin-based derivatives as an antifungal strategy.

Inhibiting Mrt4-rRNA interaction with fumaramidmycin-based derivatives as an antifungal strategy.

Journal: Nature communications

Published: November 15, 2025

Bioorthogonal Sonodynamic Plug-and-Play Targeting Chimeras (SDPTAC) for Precise Targeted Protein Degradation.

Bioorthogonal Sonodynamic Plug-and-Play Targeting Chimeras (SDPTAC) for Precise Targeted Protein Degradation.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Published: October 23, 2025

Cross-kingdom metabolic interactions govern Candida albicans overgrowth and colitis progression.

Cross-kingdom metabolic interactions govern Candida albicans overgrowth and colitis progression.

Journal: Cell host & microbe

Published: October 09, 2025

Showing 1-12 of 201

Last Updated: 09/26/2026