Chunxiao Liu

Nanjing, 211198, China

Last Updated: 09/26/2026

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Found 14 publications

Corrigendum to "Discovery of Benfotiamine as a subnanomolar P2Y14R antagonist for inflammatory diseases via drug repurposing and molecular dynamics-guided mechanism elucidation" [Eur. J. Med. Chem. 316 (2026) 119068].

Corrigendum to "Discovery of Benfotiamine as a subnanomolar P2Y14R antagonist for inflammatory diseases via drug repurposing and molecular dynamics-guided mechanism elucidation" [Eur. J. Med. Chem. 316 (2026) 119068].

Journal: European journal of medicinal chemistry

Published: July 03, 2026

Discovery of Benfotiamine as a subnanomolar P2Y14R antagonist for inflammatory diseases via drug repurposing and molecular dynamics-guided mechanism elucidation.

Discovery of Benfotiamine as a subnanomolar P2Y14R antagonist for inflammatory diseases via drug repurposing and molecular dynamics-guided mechanism elucidation.

Journal: European journal of medicinal chemistry

Published: May 14, 2026

Discovery of Novel P2Y14R Inhibitors for Ameliorating Liver Fibrosis by Suppressing Hepatic Stellate Cell Activation.

Discovery of Novel P2Y14R Inhibitors for Ameliorating Liver Fibrosis by Suppressing Hepatic Stellate Cell Activation.

Journal: Journal of medicinal chemistry

Published: November 03, 2025

Computational discovery and repurposing of chloramphenicol succinate as a potent P2Y14 receptor antagonist for inflammatory bowel disease therapy.

Computational discovery and repurposing of chloramphenicol succinate as a potent P2Y14 receptor antagonist for inflammatory bowel disease therapy.

Journal: Journal of advanced research

Published: April 20, 2025

Targeting P2Y14R alleviates platelet-induced NET formation and venous thrombosis through PKA/AKAP13/RhoA axis.

Targeting P2Y14R alleviates platelet-induced NET formation and venous thrombosis through PKA/AKAP13/RhoA axis.

Journal: European heart journal

Published: February 24, 2025

Research advances in the treatment of arthritis from natural products (2014-present).

Research advances in the treatment of arthritis from natural products (2014-present).

Journal: Chinese journal of natural medicines

Published: August 13, 2024

Attributes novel drug candidate: Constitutive GPCR signal bias mediated by purinergic receptors.

Attributes novel drug candidate: Constitutive GPCR signal bias mediated by purinergic receptors.

Journal: Pharmacology & therapeutics

Published: August 13, 2024

P2Y14R activation facilitates liver regeneration via CREB/DNMT3b/Dact-2/β-Catenin signals in acute liver failure.

P2Y14R activation facilitates liver regeneration via CREB/DNMT3b/Dact-2/β-Catenin signals in acute liver failure.

Journal: Acta pharmaceutica Sinica. B

Published: June 25, 2024

Design, Synthesis, and Biological Evaluation of a Novel NIK Inhibitor with Anti-Inflammatory and Hepatoprotective Effects for Sepsis Treatment.

Design, Synthesis, and Biological Evaluation of a Novel NIK Inhibitor with Anti-Inflammatory and Hepatoprotective Effects for Sepsis Treatment.

Journal: Journal of medicinal chemistry

Published: April 02, 2024

Macrophage P2Y6R activation aggravates psoriatic inflammation through IL-27-mediated Th1 responses.

Macrophage P2Y6R activation aggravates psoriatic inflammation through IL-27-mediated Th1 responses.

Journal: Acta pharmaceutica Sinica. B

Published: March 01, 2024

Targeting P2Y14R protects against necroptosis of intestinal epithelial cells through PKA/CREB/RIPK1 axis in ulcerative colitis.

Targeting P2Y14R protects against necroptosis of intestinal epithelial cells through PKA/CREB/RIPK1 axis in ulcerative colitis.

Journal: Nature communications

Published: January 07, 2023

GPR105-Targeted Therapy Promotes Gout Resolution as a Switch Between NETosis and Apoptosis of Neutrophils.

GPR105-Targeted Therapy Promotes Gout Resolution as a Switch Between NETosis and Apoptosis of Neutrophils.

Journal: Frontiers in immunology

Published: February 06, 2022

Showing 1-12 of 14

Last Updated: 09/26/2026