Claire Damerell-Strain

Didcot, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 39 publications

Discovery and Characterization of a Nonacidic Small-Molecule Inhibitor of the Sodium-Coupled Dicarboxylate Transporter NaCT.

Discovery and Characterization of a Nonacidic Small-Molecule Inhibitor of the Sodium-Coupled Dicarboxylate Transporter NaCT.

Journal: Journal of medicinal chemistry

Published: April 28, 2026

Substrate-Selective Inhibition of the SARS-CoV-2 Papain-Like Protease: Inhibition of Hydrolysis of Human Over Viral Substrates.

Substrate-Selective Inhibition of the SARS-CoV-2 Papain-Like Protease: Inhibition of Hydrolysis of Human Over Viral Substrates.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany)

Published: January 15, 2026

Cyclic β2,3-amino acids improve the serum stability of macrocyclic peptide inhibitors targeting the SARS-CoV-2 main protease.

Cyclic β2,3-amino acids improve the serum stability of macrocyclic peptide inhibitors targeting the SARS-CoV-2 main protease.

Journal: Bulletin of the Chemical Society of Japan

Published: December 27, 2023

Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors.

Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors.

Journal: Science (New York, N.Y.)

Published: November 09, 2023

Mass spectrometric assays monitoring the deubiquitinase activity of the SARS-CoV-2 papain-like protease inform on the basis of substrate selectivity and have utility for substrate identification.

Mass spectrometric assays monitoring the deubiquitinase activity of the SARS-CoV-2 papain-like protease inform on the basis of substrate selectivity and have utility for substrate identification.

Journal: Bioorganic & medicinal chemistry

Published: August 21, 2023

Studies on the selectivity of the SARS-CoV-2 papain-like protease reveal the importance of the P2' proline of the viral polyprotein.

Studies on the selectivity of the SARS-CoV-2 papain-like protease reveal the importance of the P2' proline of the viral polyprotein.

Journal: RSC chemical biology

Published: July 13, 2023

Accelerating drug target inhibitor discovery with a deep generative foundation model.

Accelerating drug target inhibitor discovery with a deep generative foundation model.

Journal: Science advances

Published: June 21, 2023

AI-Driven Discovery of SARS-CoV-2 Main Protease Fragment-like Inhibitors with Antiviral Activity In Vitro.

AI-Driven Discovery of SARS-CoV-2 Main Protease Fragment-like Inhibitors with Antiviral Activity In Vitro.

Journal: Journal of chemical information and modeling

Published: April 14, 2023

Architecture and regulation of filamentous human cystathionine beta-synthase.

Architecture and regulation of filamentous human cystathionine beta-synthase.

Journal: Nature communications

Published: March 31, 2023

Alkyne Derivatives of SARS-CoV-2 Main Protease Inhibitors Including Nirmatrelvir Inhibit by Reacting Covalently with the Nucleophilic Cysteine.

Alkyne Derivatives of SARS-CoV-2 Main Protease Inhibitors Including Nirmatrelvir Inhibit by Reacting Covalently with the Nucleophilic Cysteine.

Journal: Journal of medicinal chemistry

Published: February 09, 2023

Application of super-resolution and correlative double sampling in cryo-electron microscopy.

Application of super-resolution and correlative double sampling in cryo-electron microscopy.

Journal: Faraday discussions

Published: August 08, 2022

Penicillin Derivatives Inhibit the SARS-CoV-2 Main Protease by Reaction with Its Nucleophilic Cysteine.

Penicillin Derivatives Inhibit the SARS-CoV-2 Main Protease by Reaction with Its Nucleophilic Cysteine.

Journal: Journal of medicinal chemistry

Published: May 13, 2022

Showing 1-12 of 39

Last Updated: 09/26/2026