Claudia L. Flemming

Kensington, NSW, Australia

Last Updated: 09/26/2026

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Found 10 publications

CCI52 sensitizes tumors to 6-mercaptopurine and inhibits MYCN-amplified tumor growth.

CCI52 sensitizes tumors to 6-mercaptopurine and inhibits MYCN-amplified tumor growth.

Journal: Biochemical pharmacology

Published: November 12, 2019

MRP1 modulators synergize with buthionine sulfoximine to exploit collateral sensitivity and selectively kill MRP1-expressing cancer cells.

MRP1 modulators synergize with buthionine sulfoximine to exploit collateral sensitivity and selectively kill MRP1-expressing cancer cells.

Journal: Biochemical pharmacology

Published: May 10, 2019

Targeting metabolic activity in high-risk neuroblastoma through Monocarboxylate Transporter 1 (MCT1) inhibition.

Targeting metabolic activity in high-risk neuroblastoma through Monocarboxylate Transporter 1 (MCT1) inhibition.

Journal: Oncogene

Published: February 03, 2019

Inhibition of polyamine synthesis and uptake reduces tumor progression and prolongs survival in mouse models of neuroblastoma.

Inhibition of polyamine synthesis and uptake reduces tumor progression and prolongs survival in mouse models of neuroblastoma.

Journal: Science translational medicine

Published: May 16, 2018

A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction.

A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction.

Journal: Oncogene

Published: December 11, 2017

Suppression of the ATP-binding cassette transporter ABCC4 impairs neuroblastoma tumour growth and sensitises to irinotecan in vivo.

Suppression of the ATP-binding cassette transporter ABCC4 impairs neuroblastoma tumour growth and sensitises to irinotecan in vivo.

Journal: European journal of cancer (Oxford, England : 1990)

Published: May 19, 2017

MYC-Driven Neuroblastomas Are Addicted to a Telomerase-Independent Function of Dyskerin.

MYC-Driven Neuroblastomas Are Addicted to a Telomerase-Independent Function of Dyskerin.

Journal: Cancer research

Published: April 01, 2015

MYCN amplification confers enhanced folate dependence and methotrexate sensitivity in neuroblastoma.

MYCN amplification confers enhanced folate dependence and methotrexate sensitivity in neuroblastoma.

Journal: Oncotarget

Published: February 10, 2015

ABCA transporter gene expression and poor outcome in epithelial ovarian cancer.

ABCA transporter gene expression and poor outcome in epithelial ovarian cancer.

Journal: Journal of the National Cancer Institute

Published: June 25, 2014

High-throughput screening identifies Ceefourin 1 and Ceefourin 2 as highly selective inhibitors of multidrug resistance protein 4 (MRP4).

High-throughput screening identifies Ceefourin 1 and Ceefourin 2 as highly selective inhibitors of multidrug resistance protein 4 (MRP4).

Journal: Biochemical pharmacology

Published: April 04, 2014

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Last Updated: 09/26/2026