Claudia M. Saraiva

Covilha, Portugal

Last Updated: 09/26/2026

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Found 27 publications

Autophagy dysfunction in iPSCs-derived neurons and midbrain organoids carrying a SNCA triplication.

Autophagy dysfunction in iPSCs-derived neurons and midbrain organoids carrying a SNCA triplication.

Journal: NPJ Parkinson's disease
Published: August 08, 2025

Parkinson's Disease Patient-Specific Striatum Organoids Show Hallmarks of Increased Inflammation.

Parkinson's Disease Patient-Specific Striatum Organoids Show Hallmarks of Increased Inflammation.

Journal: Movement disorders : official journal of the Movement Disorder Society
Published: June 19, 2025

Deciphering shared molecular dysregulation across Parkinson's disease variants using a multi-modal network-based data integration and analysis.

Deciphering shared molecular dysregulation across Parkinson's disease variants using a multi-modal network-based data integration and analysis.

Journal: NPJ Parkinson's disease
Published: October 11, 2024

MIRO1 mutation leads to metabolic maladaptation resulting in Parkinson's disease-associated dopaminergic neuron loss.

MIRO1 mutation leads to metabolic maladaptation resulting in Parkinson's disease-associated dopaminergic neuron loss.

Journal: NPJ systems biology and applications
Published: July 26, 2024

Parkinson's disease mutant Miro1 causes mitochondrial dysfunction and dopaminergic neuron loss.

Parkinson's disease mutant Miro1 causes mitochondrial dysfunction and dopaminergic neuron loss.

Journal: Brain : a journal of neurology
Published: July 10, 2024

Modeling early phenotypes of Parkinson's disease by age-induced midbrain-striatum assembloids.

Modeling early phenotypes of Parkinson's disease by age-induced midbrain-striatum assembloids.

Journal: Communications biology
Published: June 20, 2024

Author Correction: Efficient spatially targeted gene editing using a near-infrared activatable protein-conjugated nanoparticle for brain applications.

Author Correction: Efficient spatially targeted gene editing using a near-infrared activatable protein-conjugated nanoparticle for brain applications.

Journal: Nature communications
Published: July 17, 2023

Generation of two induced pluripotent stem cell lines and the corresponding isogenic controls from Parkinson's disease patients carrying the heterozygous mutations c.1290A > G (p.T351A) or c.2067A > G (p.T610A) in the RHOT1 gene encoding Miro1.

Generation of two induced pluripotent stem cell lines and the corresponding isogenic controls from Parkinson's disease patients carrying the heterozygous mutations c.1290A > G (p.T351A) or c.2067A > G (p.T610A) in the RHOT1 gene encoding Miro1.

Journal: Stem cell research
Published: February 27, 2023

Impaired neuron differentiation in GBA-associated Parkinson's disease is linked to cell cycle defects in organoids.

Impaired neuron differentiation in GBA-associated Parkinson's disease is linked to cell cycle defects in organoids.

Journal: NPJ Parkinson's disease
Published: January 12, 2023

CtBP Neuroprotective Role in Toxin-Based Parkinson's Disease Models: From Expression Pattern to Dopaminergic Survival.

CtBP Neuroprotective Role in Toxin-Based Parkinson's Disease Models: From Expression Pattern to Dopaminergic Survival.

Journal: Molecular neurobiology
Published: June 09, 2022

Gold nanostructures: synthesis, properties, and neurological applications.

Gold nanostructures: synthesis, properties, and neurological applications.

Journal: Chemical Society reviews
Published: March 02, 2022

Microglia integration into human midbrain organoids leads to increased neuronal maturation and functionality.

Microglia integration into human midbrain organoids leads to increased neuronal maturation and functionality.

Journal: Glia
Published: January 21, 2022
Showing 1-12 of 27

Last Updated: 09/26/2026