Claudia Sorbi

Modena, Italy

Last Updated: 09/26/2026

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Found 21 publications

Purine and Pyrrolopyrimidine-Based Small Molecules as Multitarget Therapeutics.

Purine and Pyrrolopyrimidine-Based Small Molecules as Multitarget Therapeutics.

Journal: Archiv der Pharmazie

Published: August 20, 2025

Structure-Based Discovery of Hsp90/HDAC6 Dual Inhibitors Targeting Aggressive Prostate Cancer.

Structure-Based Discovery of Hsp90/HDAC6 Dual Inhibitors Targeting Aggressive Prostate Cancer.

Journal: Journal of medicinal chemistry

Published: July 23, 2025

1,3-Dithiolane as a Privileged Scaffold in Bioactive Derivatives: Chiral Resolution and Assignment of Absolute Configuration.

1,3-Dithiolane as a Privileged Scaffold in Bioactive Derivatives: Chiral Resolution and Assignment of Absolute Configuration.

Journal: International journal of molecular sciences

Published: October 29, 2024

Discovery of potent pyrrolo-pyrimidine and purine HDAC inhibitors for the treatment of advanced prostate cancer.

Discovery of potent pyrrolo-pyrimidine and purine HDAC inhibitors for the treatment of advanced prostate cancer.

Journal: European journal of medicinal chemistry

Published: June 01, 2023

Insights into the Structural Conformations of the Tau Protein in Different Aggregation Status.

Insights into the Structural Conformations of the Tau Protein in Different Aggregation Status.

Journal: Molecules (Basel, Switzerland)

Published: March 29, 2023

BS148 Reduces the Aggressiveness of Metastatic Melanoma via Sigma-2 Receptor Targeting.

BS148 Reduces the Aggressiveness of Metastatic Melanoma via Sigma-2 Receptor Targeting.

Journal: International journal of molecular sciences

Published: March 21, 2023

Novel S1R agonists counteracting NMDA excitotoxicity and oxidative stress: A step forward in the discovery of neuroprotective agents.

Novel S1R agonists counteracting NMDA excitotoxicity and oxidative stress: A step forward in the discovery of neuroprotective agents.

Journal: European journal of medicinal chemistry

Published: November 09, 2022

Inhibitors of histone deacetylase 6 based on a novel 3-hydroxy-isoxazole zinc binding group.

Inhibitors of histone deacetylase 6 based on a novel 3-hydroxy-isoxazole zinc binding group.

Journal: Journal of enzyme inhibition and medicinal chemistry

Published: September 29, 2021

Identification of a Potent and Selective 5-HT1A Receptor Agonist with In Vitro and In Vivo Antinociceptive Activity.

Identification of a Potent and Selective 5-HT1A Receptor Agonist with In Vitro and In Vivo Antinociceptive Activity.

Journal: ACS chemical neuroscience

Published: December 02, 2020

Investigation of the effect of different linker chemotypes on the inhibition of histone deacetylases (HDACs).

Investigation of the effect of different linker chemotypes on the inhibition of histone deacetylases (HDACs).

Journal: Bioorganic chemistry

Published: August 08, 2020

Novel Dithiolane-Based Ligands Combining Sigma and NMDA Receptor Interactions as Potential Neuroprotective Agents.

Novel Dithiolane-Based Ligands Combining Sigma and NMDA Receptor Interactions as Potential Neuroprotective Agents.

Journal: ACS medicinal chemistry letters

Published: March 15, 2020

Spiroxatrine derivatives towards 5-HT1A receptor selectivity.

Spiroxatrine derivatives towards 5-HT1A receptor selectivity.

Journal: Pharmacological reports : PR

Published: July 03, 2019

Showing 1-12 of 21

Last Updated: 09/26/2026