Con Panousis

30 Flemington Road
Parkville, VIC 3010, Australia

Last Updated: 09/26/2026

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Found 28 publications

Structural basis for the inhibition of βFXIIa by garadacimab.

Structural basis for the inhibition of βFXIIa by garadacimab.

Journal: Structure (London, England : 1993)

Published: April 04, 2024

A mechanistic model of in vitro plasma activation to evaluate therapeutic kallikrein-kinin system inhibitors.

A mechanistic model of in vitro plasma activation to evaluate therapeutic kallikrein-kinin system inhibitors.

Journal: PLoS computational biology

Published: January 29, 2024

High-Throughput IgG Reformatting and Expression Using Hybrid Secretion Signals and InTag Positive Selection Technology.

High-Throughput IgG Reformatting and Expression Using Hybrid Secretion Signals and InTag Positive Selection Technology.

Journal: Methods in molecular biology (Clifton, N.J.)

Published: September 07, 2023

Activated Coagulation FXII: A Unique Target for In Vivo Molecular Imaging.

Activated Coagulation FXII: A Unique Target for In Vivo Molecular Imaging.

Journal: Arteriosclerosis, thrombosis, and vascular biology

Published: April 20, 2023

HDX-MS study on garadacimab binding to activated FXII reveals potential binding interfaces through differential solvent exposure.

HDX-MS study on garadacimab binding to activated FXII reveals potential binding interfaces through differential solvent exposure.

Journal: mAbs

Published: January 11, 2023

Evaluation of Phage Display Biopanning Strategies for the Selection of Anti-Cell Surface Receptor Antibodies.

Evaluation of Phage Display Biopanning Strategies for the Selection of Anti-Cell Surface Receptor Antibodies.

Journal: International journal of molecular sciences

Published: June 30, 2022

Coagulation factor-XII induces interleukin-6 by primary lung fibroblasts: a role in idiopathic pulmonary fibrosis?

Coagulation factor-XII induces interleukin-6 by primary lung fibroblasts: a role in idiopathic pulmonary fibrosis?

Journal: American journal of physiology. Lung cellular and molecular physiology

Published: December 07, 2021

Pharmacological Inhibition of Factor XIIa Attenuates Abdominal Aortic Aneurysm, Reduces Atherosclerosis, and Stabilizes Atherosclerotic Plaques.

Pharmacological Inhibition of Factor XIIa Attenuates Abdominal Aortic Aneurysm, Reduces Atherosclerosis, and Stabilizes Atherosclerotic Plaques.

Journal: Thrombosis and haemostasis

Published: October 07, 2021

A phase I, first-in-human, randomized dose-escalation study of anti-activated factor XII monoclonal antibody garadacimab.

A phase I, first-in-human, randomized dose-escalation study of anti-activated factor XII monoclonal antibody garadacimab.

Journal: Clinical and translational science

Published: June 30, 2021

Generation of a humanized FXII knock-in mouse-A powerful model system to test novel anti-thrombotic agents.

Generation of a humanized FXII knock-in mouse-A powerful model system to test novel anti-thrombotic agents.

Journal: Journal of thrombosis and haemostasis : JTH

Published: April 06, 2021

Increased potency of recombinant VWF D'D3 albumin fusion proteins engineered for enhanced affinity for coagulation factor VIII.

Increased potency of recombinant VWF D'D3 albumin fusion proteins engineered for enhanced affinity for coagulation factor VIII.

Journal: Journal of thrombosis and haemostasis : JTH

Published: December 02, 2020

A novel soluble complement receptor 1 fragment with enhanced therapeutic potential.

A novel soluble complement receptor 1 fragment with enhanced therapeutic potential.

Journal: The Journal of biological chemistry

Published: September 22, 2020

Showing 1-12 of 28

Last Updated: 09/26/2026