Constanze Bonifer

50 Flemington Road
Parkville, VIC 3052, Australia

Last Updated: 09/26/2026

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Found 87 publications

Mechanistic insights into gene regulation driving normal and malignant hematopoietic development from embryonic and induced pluripotent stem cell differentiation.

Mechanistic insights into gene regulation driving normal and malignant hematopoietic development from embryonic and induced pluripotent stem cell differentiation.

Journal: Experimental hematology
Published: March 12, 2026

Fusion gene depletion eliminates stemness and induces bidirectional differentiation of acute myeloid leukemia.

Fusion gene depletion eliminates stemness and induces bidirectional differentiation of acute myeloid leukemia.

Journal: Blood
Published: February 25, 2025

Regulation of developmentally controlled enhancer activity by extrinsic signals in normal and malignant cells: AP-1 at the centre.

Regulation of developmentally controlled enhancer activity by extrinsic signals in normal and malignant cells: AP-1 at the centre.

Journal: Frontiers in epigenetics and epigenomics
Published: November 07, 2024

Gene regulatory network and signalling pathway rewiring: How blood cancer cells shift their shapes to evade drug treatment.

Gene regulatory network and signalling pathway rewiring: How blood cancer cells shift their shapes to evade drug treatment.

Journal: Oncotarget
Published: October 11, 2024

Fusion-specific chromatin profiles mediate transcriptional heterogeneity in MLL-rearranged acute lymphoblastic leukemia.

Fusion-specific chromatin profiles mediate transcriptional heterogeneity in MLL-rearranged acute lymphoblastic leukemia.

Journal: Blood advances
Published: June 25, 2024

Pharmacological inhibition of RAS overcomes FLT3 inhibitor resistance in FLT3-ITD+ AML through AP-1 and RUNX1.

Pharmacological inhibition of RAS overcomes FLT3 inhibitor resistance in FLT3-ITD+ AML through AP-1 and RUNX1.

Journal: iScience
Published: October 23, 2023

Genome-scale clustered regularly interspaced short palindromic repeats screen identifies nucleotide metabolism as an actionable therapeutic vulnerability in diffuse large B-cell lymphoma.

Genome-scale clustered regularly interspaced short palindromic repeats screen identifies nucleotide metabolism as an actionable therapeutic vulnerability in diffuse large B-cell lymphoma.

Journal: Haematologica
Published: October 04, 2023

Chromatin priming elements direct tissue-specific gene activity before hematopoietic specification.

Chromatin priming elements direct tissue-specific gene activity before hematopoietic specification.

Journal: Life science alliance
Published: September 11, 2023

Gene regulation in t(6;9) DEK::NUP214 Acute Myeloid Leukemia resembles that of FLT3-ITD/NPM1 Acute Myeloid Leukemia but with an altered HOX/MEIS axis.

Gene regulation in t(6;9) DEK::NUP214 Acute Myeloid Leukemia resembles that of FLT3-ITD/NPM1 Acute Myeloid Leukemia but with an altered HOX/MEIS axis.

Journal: Leukemia
Published: August 21, 2023

A heterozygous CEBPA mutation disrupting the bZIP domain in a RUNX1 and SRSF2 mutational background causes MDS disease progression.

A heterozygous CEBPA mutation disrupting the bZIP domain in a RUNX1 and SRSF2 mutational background causes MDS disease progression.

Journal: Nature communications
Published: August 02, 2023

Gene regulatory network analysis predicts cooperating transcription factor regulons required for FLT3-ITD+ AML growth.

Gene regulatory network analysis predicts cooperating transcription factor regulons required for FLT3-ITD+ AML growth.

Journal: bioRxiv : the preprint server for biology
Published: July 28, 2023

Gene regulatory network analysis predicts cooperating transcription factor regulons required for FLT3-ITD+ AML growth.

Gene regulatory network analysis predicts cooperating transcription factor regulons required for FLT3-ITD+ AML growth.

Journal: Cell reports
Published: July 13, 2023
Showing 1-12 of 87

Last Updated: 09/26/2026