Constanze Knebel

Max Dohrn Street 8-10
Berlin, BE 10589, Germany

Last Updated: 09/26/2026

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Found 9 publications

New Approach Methods for Hazard Identification: A Case Study with Azole Fungicides Affecting Molecular Targets Associated with the Adverse Outcome Pathway for Cholestasis.

New Approach Methods for Hazard Identification: A Case Study with Azole Fungicides Affecting Molecular Targets Associated with the Adverse Outcome Pathway for Cholestasis.

Journal: Cells

Published: August 18, 2022

The Connection of Azole Fungicides with Xeno-Sensing Nuclear Receptors, Drug Metabolism and Hepatotoxicity.

The Connection of Azole Fungicides with Xeno-Sensing Nuclear Receptors, Drug Metabolism and Hepatotoxicity.

Journal: Cells

Published: April 24, 2020

Induction and repression effects on CYP and transporter protein abundance by azole mixture uptake in rat liver.

Induction and repression effects on CYP and transporter protein abundance by azole mixture uptake in rat liver.

Journal: EXCLI journal

Published: April 20, 2020

Assessment of mixture toxicity of (tri)azoles and their hepatotoxic effects in vitro by means of omics technologies.

Assessment of mixture toxicity of (tri)azoles and their hepatotoxic effects in vitro by means of omics technologies.

Journal: Archives of toxicology

Published: April 26, 2019

Pregnane X receptor mediates steatotic effects of propiconazole and tebuconazole in human liver cell lines.

Pregnane X receptor mediates steatotic effects of propiconazole and tebuconazole in human liver cell lines.

Journal: Archives of toxicology

Published: February 18, 2019

The azole fungicide tebuconazole affects human CYP1A1 and CYP1A2 expression by an aryl hydrocarbon receptor-dependent pathway.

The azole fungicide tebuconazole affects human CYP1A1 and CYP1A2 expression by an aryl hydrocarbon receptor-dependent pathway.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

Published: October 15, 2018

Propiconazole is an activator of AHR and causes concentration additive effects with an established AHR ligand.

Propiconazole is an activator of AHR and causes concentration additive effects with an established AHR ligand.

Journal: Archives of toxicology

Published: June 15, 2018

Unexpected Effects of Propiconazole, Tebuconazole, and Their Mixture on the Receptors CAR and PXR in Human Liver Cells.

Unexpected Effects of Propiconazole, Tebuconazole, and Their Mixture on the Receptors CAR and PXR in Human Liver Cells.

Journal: Toxicological sciences : an official journal of the Society of Toxicology

Published: February 09, 2018

Hepatotoxic effects of cyproconazole and prochloraz in wild-type and hCAR/hPXR mice.

Hepatotoxic effects of cyproconazole and prochloraz in wild-type and hCAR/hPXR mice.

Journal: Archives of toxicology

Published: September 02, 2016

Showing 1-9 of 9

Last Updated: 09/26/2026