Last Updated: 09/26/2026
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Found 10 publications
Biochemical and structural basis for the pharmacological inhibition of nuclear hormone receptor PPARγ by inverse agonists.
Journal: The Journal of biological chemistry
Published: July 26, 2022
Combined inhibition of FGFR4 and VEGFR signaling enhances efficacy in FGF19 driven hepatocellular carcinoma.
Journal: American journal of cancer research
Published: February 08, 2022
Discovery of Aminopyrazole Derivatives as Potent Inhibitors of Wild-Type and Gatekeeper Mutant FGFR2 and 3.
Journal: ACS medicinal chemistry letters
Published: September 25, 2020
The cryo-EM structure of the SF3b spliceosome complex bound to a splicing modulator reveals a pre-mRNA substrate competitive mechanism of action.
Journal: Genes & development
Published: December 20, 2017
H3B-6527 Is a Potent and Selective Inhibitor of FGFR4 in FGF19-Driven Hepatocellular Carcinoma.
Journal: Cancer research
Published: June 22, 2017
Splicing modulators act at the branch point adenosine binding pocket defined by the PHF5A-SF3b complex.
Journal: Nature communications
Published: December 12, 2016
Showing 1-10 of 10
Last Updated: 09/26/2026