Last Updated: 09/26/2026
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Found 11 publications
A novel plasmid-based co-tethered transcription platform for high yield, high purity mRNA synthesis.
A novel plasmid-based co-tethered transcription platform for high yield, high purity mRNA synthesis.
Journal: Nucleic acids research
Published: August 14, 2025
A new approach to RNA synthesis: immobilization of stably and functionally co-tethered promoter DNA and T7 RNA polymerase.
Journal: Nucleic acids research
Published: March 25, 2024
A simple approach to improving RNA synthesis: Salt inhibition of RNA rebinding coupled with strengthening promoter binding by a targeted gap in the DNA.
Journal: Methods in enzymology
Published: November 01, 2023
High-salt transcription from enzymatically gapped promoters nets higher yields and purity of transcribed RNAs.
Journal: Nucleic acids research
Published: February 28, 2022
High-salt transcription of DNA cotethered with T7 RNA polymerase to beads generates increased yields of highly pure RNA.
Journal: The Journal of biological chemistry
Published: April 29, 2021
Efficient inhibition of RNA self-primed extension by addition of competing 3'-capture DNA-improved RNA synthesis by T7 RNA polymerase.
Journal: Nucleic acids research
Published: May 17, 2019
Closed for business: exit-channel coupling to active site conformation in bacterial RNA polymerase.
Journal: Nature structural & molecular biology
Published: September 06, 2014
Insights into the mechanism of initial transcription in Escherichia coli RNA polymerase.
Journal: The Journal of biological chemistry
Published: September 20, 2013
New insights into the mechanism of initial transcription: the T7 RNA polymerase mutant P266L transitions to elongation at longer RNA lengths than wild type.
Journal: The Journal of biological chemistry
Published: August 28, 2012
Transcription elongation complex stability: the topological lock.
Journal: The Journal of biological chemistry
Published: October 23, 2009
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Last Updated: 09/26/2026