Cristian O. Salas

Santiago, RM, Chile

Last Updated: 09/26/2026

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Found 47 publications

Purine derivatives as potential agents against Chagas disease: Ex vivo, in vitro, in silico evaluation, and identification of targets in Trypanosoma cruzi.

Purine derivatives as potential agents against Chagas disease: Ex vivo, in vitro, in silico evaluation, and identification of targets in Trypanosoma cruzi.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Published: April 20, 2026

Experimental and In Silico Studies to Unravel the Antioxidant and Antibacterial Properties of Lichen Metabolites from Pseudocyphellaria compar and Pseudocyphellaria nudata.

Experimental and In Silico Studies to Unravel the Antioxidant and Antibacterial Properties of Lichen Metabolites from Pseudocyphellaria compar and Pseudocyphellaria nudata.

Journal: Antioxidants (Basel, Switzerland)

Published: December 01, 2025

New pyrimidine derivatives as potential agents against hepatocellular carcinoma: design, synthesis, and in vitro and in vivo biological evaluations.

New pyrimidine derivatives as potential agents against hepatocellular carcinoma: design, synthesis, and in vitro and in vivo biological evaluations.

Journal: Frontiers in pharmacology

Published: November 12, 2025

Structure-Guided Discovery of Benzoic-Acid-Based TRPC6 Ligands: An Integrated Docking, MD, and MM-GBSA SAR Study: Potential Therapeutic Molecules for Autism Spectrum Disorder.

Structure-Guided Discovery of Benzoic-Acid-Based TRPC6 Ligands: An Integrated Docking, MD, and MM-GBSA SAR Study: Potential Therapeutic Molecules for Autism Spectrum Disorder.

Journal: Pharmaceuticals (Basel, Switzerland)

Published: September 04, 2025

3D-QSAR Design of New Bcr-Abl Inhibitors Based on Purine Scaffold and Cytotoxicity Studies on CML Cell Lines Sensitive and Resistant to Imatinib.

3D-QSAR Design of New Bcr-Abl Inhibitors Based on Purine Scaffold and Cytotoxicity Studies on CML Cell Lines Sensitive and Resistant to Imatinib.

Journal: Pharmaceuticals (Basel, Switzerland)

Published: May 20, 2025

New Dimethoxyaryl-Sesquiterpene Derivatives with Cytotoxic Activity Against MCF-7 Breast Cancer Cells: From Synthesis to Topoisomerase I/II Inhibition and Cell Death Mechanism Studies.

New Dimethoxyaryl-Sesquiterpene Derivatives with Cytotoxic Activity Against MCF-7 Breast Cancer Cells: From Synthesis to Topoisomerase I/II Inhibition and Cell Death Mechanism Studies.

Journal: International journal of molecular sciences

Published: April 11, 2025

Editorial: Exploring novel approaches to small molecule kinase inhibitors in cancer treatment.

Editorial: Exploring novel approaches to small molecule kinase inhibitors in cancer treatment.

Journal: Frontiers in chemistry

Published: January 13, 2025

First Report on Cationic Triphenylphosphonium Compounds as Mitochondriotropic H3R Ligands with Antioxidant Properties.

First Report on Cationic Triphenylphosphonium Compounds as Mitochondriotropic H3R Ligands with Antioxidant Properties.

Journal: Antioxidants (Basel, Switzerland)

Published: September 30, 2024

First in class pyrrolo[2,3-d]pyrimidine derivatives fused to fluorobenzylpiperidines as dual ligands of acetylcholinesterase and histamine H3 receptor.

First in class pyrrolo[2,3-d]pyrimidine derivatives fused to fluorobenzylpiperidines as dual ligands of acetylcholinesterase and histamine H3 receptor.

Journal: Archiv der Pharmazie

Published: May 17, 2024

New Inhibitors of Bcr-Abl Based on 2,6,9-Trisubstituted Purine Scaffold Elicit Cytotoxicity in Chronic Myeloid Leukemia-Derived Cell Lines Sensitive and Resistant to TKIs.

New Inhibitors of Bcr-Abl Based on 2,6,9-Trisubstituted Purine Scaffold Elicit Cytotoxicity in Chronic Myeloid Leukemia-Derived Cell Lines Sensitive and Resistant to TKIs.

Journal: Pharmaceutics

Published: April 08, 2024

New Smoothened ligands based on the purine scaffold as potential agents for treating pancreatic cancer.

New Smoothened ligands based on the purine scaffold as potential agents for treating pancreatic cancer.

Journal: Bioorganic chemistry

Published: March 28, 2024

In vitro and In vivo Biological Activity of Two Aryloxy-naphthoquinones in Mice Infected with Trypanosoma cruzi Strains.

In vitro and In vivo Biological Activity of Two Aryloxy-naphthoquinones in Mice Infected with Trypanosoma cruzi Strains.

Journal: Medicinal chemistry (Shariqah (United Arab Emirates))

Published: January 24, 2024

Showing 1-12 of 47

Last Updated: 09/26/2026