Cristobal De Los Rios

Alcorcon, MD, Spain

Last Updated: 09/26/2026

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Found 55 publications

Pharmacological evaluation of non-nucleotide purine derivatives as P2X7 antagonists for the treatment of neuroinflammation in traumatic brain injury.

Pharmacological evaluation of non-nucleotide purine derivatives as P2X7 antagonists for the treatment of neuroinflammation in traumatic brain injury.

Journal: British journal of pharmacology

Published: September 25, 2024

Retinal response to systemic inflammation differs between sexes and neurons.

Retinal response to systemic inflammation differs between sexes and neurons.

Journal: Frontiers in immunology

Published: November 17, 2023

Evaluation of the neuroprotective efficacy of the gramine derivative ITH12657 against NMDA-induced excitotoxicity in the rat retina.

Evaluation of the neuroprotective efficacy of the gramine derivative ITH12657 against NMDA-induced excitotoxicity in the rat retina.

Journal: Frontiers in neuroanatomy

Published: November 08, 2023

Melatonin as Modulator for Sulfur and Nitrogen Mustard-Induced Inflammation, Oxidative Stress and DNA Damage: Molecular Therapeutics.

Melatonin as Modulator for Sulfur and Nitrogen Mustard-Induced Inflammation, Oxidative Stress and DNA Damage: Molecular Therapeutics.

Journal: Antioxidants (Basel, Switzerland)

Published: December 10, 2022

Promising Molecular Targets in Pharmacological Therapy for Neuronal Damage in Brain Injury.

Promising Molecular Targets in Pharmacological Therapy for Neuronal Damage in Brain Injury.

Journal: Antioxidants (Basel, Switzerland)

Published: November 24, 2022

C-glycosides analogues of the okadaic acid central fragment exert neuroprotection via restoration of PP2A-phosphatase activity: A rational design of potential drugs for Alzheimer's disease targeting tauopathies.

C-glycosides analogues of the okadaic acid central fragment exert neuroprotection via restoration of PP2A-phosphatase activity: A rational design of potential drugs for Alzheimer's disease targeting tauopathies.

Journal: European journal of medicinal chemistry

Published: October 31, 2022

Polyfunctionalized α-Phenyl-tert-butyl(benzyl)nitrones: Multifunctional Antioxidants for Stroke Treatment.

Polyfunctionalized α-Phenyl-tert-butyl(benzyl)nitrones: Multifunctional Antioxidants for Stroke Treatment.

Journal: Antioxidants (Basel, Switzerland)

Published: August 09, 2022

Cellulose/pectin-based materials incorporating Laponite-indole derivative hybrid for oral administration and controlled delivery of the neuroprotective drug.

Cellulose/pectin-based materials incorporating Laponite-indole derivative hybrid for oral administration and controlled delivery of the neuroprotective drug.

Journal: International journal of biological macromolecules

Published: August 04, 2022

Targeting neuronal calcium channels and GSK3β for Alzheimer's disease with naturally-inspired Diels-Alder adducts.

Targeting neuronal calcium channels and GSK3β for Alzheimer's disease with naturally-inspired Diels-Alder adducts.

Journal: Bioorganic chemistry

Published: July 26, 2022

Dual Role of the P2X7 Receptor in Dendritic Outgrowth during Physiological and Pathological Brain Development.

Dual Role of the P2X7 Receptor in Dendritic Outgrowth during Physiological and Pathological Brain Development.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience

Published: April 22, 2022

Novel Purine Derivative ITH15004 Facilitates Exocytosis through a Mitochondrial Calcium-Mediated Mechanism.

Novel Purine Derivative ITH15004 Facilitates Exocytosis through a Mitochondrial Calcium-Mediated Mechanism.

Journal: International journal of molecular sciences

Published: December 06, 2021

Increased expression of the ATP-gated P2X7 receptor reduces responsiveness to anti-convulsants during status epilepticus in mice.

Increased expression of the ATP-gated P2X7 receptor reduces responsiveness to anti-convulsants during status epilepticus in mice.

Journal: British journal of pharmacology

Published: August 28, 2021

Showing 1-12 of 55

Last Updated: 09/26/2026