Da-fang Zhong

State Key Laboratory Of Drug Research
Shanghai, China

Last Updated: 09/26/2026

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Found 51 publications

Investigation of absorption, metabolism, and excretion of [14C]pruxelutamide (GT0918), an androgen receptor antagonist in humans.

Investigation of absorption, metabolism, and excretion of [14C]pruxelutamide (GT0918), an androgen receptor antagonist in humans.

Journal: British journal of clinical pharmacology

Published: August 20, 2024

Author Correction: Pharmacokinetics, mass balance, and metabolism of [14C]vicagrel, a novel irreversible P2Y12 inhibitor in humans.

Author Correction: Pharmacokinetics, mass balance, and metabolism of [14C]vicagrel, a novel irreversible P2Y12 inhibitor in humans.

Journal: Acta pharmacologica Sinica

Published: August 02, 2023

Absorption, distribution, metabolism, and excretion of [14C]TPN729 after oral administration to rats.

Absorption, distribution, metabolism, and excretion of [14C]TPN729 after oral administration to rats.

Journal: Xenobiotica; the fate of foreign compounds in biological systems

Published: January 18, 2022

Effect of autoinduction and food on the pharmacokinetics of furmonertinib and its active metabolite characterized by a population pharmacokinetic model.

Effect of autoinduction and food on the pharmacokinetics of furmonertinib and its active metabolite characterized by a population pharmacokinetic model.

Journal: Acta pharmacologica Sinica

Published: June 10, 2021

Effects of Food on the Pharmacokinetic Properties and Mass Balance of Henagliflozin in Healthy Male Volunteers.

Effects of Food on the Pharmacokinetic Properties and Mass Balance of Henagliflozin in Healthy Male Volunteers.

Journal: Clinical therapeutics

Published: April 20, 2021

Furmonertinib (Alflutinib, AST2818) is a potential positive control drug comparable to rifampin for evaluation of CYP3A4 induction in sandwich-cultured primary human hepatocytes.

Furmonertinib (Alflutinib, AST2818) is a potential positive control drug comparable to rifampin for evaluation of CYP3A4 induction in sandwich-cultured primary human hepatocytes.

Journal: Acta pharmacologica Sinica

Published: January 12, 2021

Tolerability, Pharmacokinetic, and Pharmacodynamic Profiles of Henagliflozin, a Novel Selective Inhibitor of Sodium-Glucose Cotransporter 2, in Healthy Subjects Following Single- and Multiple-dose Administration.

Tolerability, Pharmacokinetic, and Pharmacodynamic Profiles of Henagliflozin, a Novel Selective Inhibitor of Sodium-Glucose Cotransporter 2, in Healthy Subjects Following Single- and Multiple-dose Administration.

Journal: Clinical therapeutics

Published: October 13, 2020

Metabolic disposition of the EGFR covalent inhibitor furmonertinib in humans.

Metabolic disposition of the EGFR covalent inhibitor furmonertinib in humans.

Journal: Acta pharmacologica Sinica

Published: October 08, 2020

Simultaneous determination of forsythin and its major metabolites in human plasma via liquid chromatography-tandem mass spectrometry.

Simultaneous determination of forsythin and its major metabolites in human plasma via liquid chromatography-tandem mass spectrometry.

Journal: Journal of pharmaceutical and biomedical analysis

Published: August 28, 2020

Effects of rifampicin on the pharmacokinetics of alflutinib, a selective third-generation EGFR kinase inhibitor, and its metabolite AST5902 in healthy volunteers.

Effects of rifampicin on the pharmacokinetics of alflutinib, a selective third-generation EGFR kinase inhibitor, and its metabolite AST5902 in healthy volunteers.

Journal: Investigational new drugs

Published: August 23, 2020

Pharmacokinetics, mass balance, and metabolism of [14C]vicagrel, a novel irreversible P2Y12 inhibitor in humans.

Pharmacokinetics, mass balance, and metabolism of [14C]vicagrel, a novel irreversible P2Y12 inhibitor in humans.

Journal: Acta pharmacologica Sinica

Published: June 23, 2020

Sulfation predominates the pharmacokinetics, metabolism, and excretion of forsythin in humans: major enzymes and transporters identified.

Sulfation predominates the pharmacokinetics, metabolism, and excretion of forsythin in humans: major enzymes and transporters identified.

Journal: Acta pharmacologica Sinica

Published: March 31, 2020

Showing 1-12 of 51

Last Updated: 09/26/2026