Dae G. Kim
Incheon, Republic of Korea
Last Updated: 09/26/2026
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Found 26 publications
Chemical induction of the interaction between AIMP2-DX2 and Siah1 to enhance ubiquitination.
Journal: Cell chemical biology
Published: January 11, 2023
Synthesis and discovery of the first potent proteolysis targeting chimaera (PROTAC) degrader of AIMP2-DX2 as a lung cancer drug.
Journal: Journal of enzyme inhibition and medicinal chemistry
Published: October 28, 2022
Allosteric Inhibition of the Tumor-Promoting Interaction Between Exon 2-Depleted Splice Variant of Aminoacyl-Transfer RNA Synthetase-Interacting Multifunctional Protein 2 and Heat Shock Protein 70.
Journal: The Journal of pharmacology and experimental therapeutics
Published: May 27, 2021
AIMP2-DX2 provides therapeutic interface to control KRAS-driven tumorigenesis.
Journal: Nature communications
Published: May 18, 2021
Anticancer Activity of Pyrimethamine via Ubiquitin Mediated Degradation of AIMP2-DX2.
Journal: Molecules (Basel, Switzerland)
Published: May 15, 2020
An Isoform of the Oncogenic Splice Variant AIMP2-DX2 Detected by a Novel Monoclonal Antibody.
Journal: Biomolecules
Published: May 08, 2020
Synthesis and Structure-Activity Relationships of Arylsulfonamides as AIMP2-DX2 Inhibitors for the Development of a Novel Anticancer Therapy.
Journal: Journal of medicinal chemistry
Published: April 22, 2020
2-Aminophenylpyrimidines as Novel Inhibitors of Aminoacyl-tRNA Synthetase Interacting Multifunctional Protein 2 (AIMP2)-DX2 for Lung Cancer Treatment.
Journal: Journal of medicinal chemistry
Published: March 27, 2020
ERK-dependent phosphorylation of the linker and substrate-binding domain of HSP70 increases folding activity and cell proliferation.
Journal: Experimental & molecular medicine
Published: April 08, 2019
Targeting the interaction of AIMP2-DX2 with HSP70 suppresses cancer development.
Journal: Nature chemical biology
Published: March 04, 2019
Data on optimization of expression and purification of AIMP2-DX2 protein in Escherichia coli.
Journal: Data in brief
Published: February 03, 2017
Purification and biophysical characterization of the AIMP2-DX2 protein.
Journal: Protein expression and purification
Published: December 23, 2016
Last Updated: 09/26/2026