Damian J. Krysan

Infectious Disease
200 Hawkins Dr
Iowa City, IA 52242

Last Updated: 09/26/2026

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Found 111 publications

The transcription factor Ahr1 governs the recruitment of neutrophils to the brain and clearance of Candida albicans during CNS infection.

The transcription factor Ahr1 governs the recruitment of neutrophils to the brain and clearance of Candida albicans during CNS infection.

Journal: mBio
Published: July 20, 2026

Cryptococcus neoformans adapts to host CO2 concentrations through the coordinated remodeling of central carbon metabolism, oxidative stress resistance, and membrane homeostasis.

Cryptococcus neoformans adapts to host CO2 concentrations through the coordinated remodeling of central carbon metabolism, oxidative stress resistance, and membrane homeostasis.

Journal: bioRxiv : the preprint server for biology
Published: December 15, 2025

Cryptococcus neoformans adapts to host CO2 concentrations via metabolic and stress-response remodeling.

Cryptococcus neoformans adapts to host CO2 concentrations via metabolic and stress-response remodeling.

Journal: PLoS biology
Published: November 13, 2025

The Candida albicans transcription factor Efg1 governs hyphal morphogenesis independently of the cAMP-protein kinase A pathway.

The Candida albicans transcription factor Efg1 governs hyphal morphogenesis independently of the cAMP-protein kinase A pathway.

Journal: mBio
Published: October 31, 2025

Second generation repurposing of phenothiazine antipsychotic drugs as antifungal lead molecules via optimization of phenoxazine derivatives.

Second generation repurposing of phenothiazine antipsychotic drugs as antifungal lead molecules via optimization of phenoxazine derivatives.

Journal: European journal of medicinal chemistry
Published: September 02, 2025

Host-induced climate change: Carbon dioxide tolerance as a Cryptococcus neoformans virulence trait.

Host-induced climate change: Carbon dioxide tolerance as a Cryptococcus neoformans virulence trait.

Journal: PLoS pathogens
Published: August 08, 2025

Synthesis and evaluation of acyl-AMP phosphate isosteres as inhibitors of fungal acetyl CoA synthetase.

Synthesis and evaluation of acyl-AMP phosphate isosteres as inhibitors of fungal acetyl CoA synthetase.

Journal: Bioorganic & medicinal chemistry letters
Published: April 01, 2025

Discovery and mechanism of a highly selective, antifungal acetyl CoA synthetase inhibitor.

Discovery and mechanism of a highly selective, antifungal acetyl CoA synthetase inhibitor.

Journal: Research square
Published: January 13, 2025

Genetic interaction analysis of Candida glabrata transcription factors CST6 and UPC2A in the regulation of respiration and fluconazole susceptibility.

Genetic interaction analysis of Candida glabrata transcription factors CST6 and UPC2A in the regulation of respiration and fluconazole susceptibility.

Journal: Antimicrobial agents and chemotherapy
Published: December 23, 2024

Discovery and mechanism of a highly selective, antifungal acetyl-CoA synthetase inhibitor.

Discovery and mechanism of a highly selective, antifungal acetyl-CoA synthetase inhibitor.

Journal: Nature communications
Published: December 10, 2024

Similarities and distinctions in the activation of the Candida glabrata Pdr1 regulatory pathway by azole and non-azole drugs.

Similarities and distinctions in the activation of the Candida glabrata Pdr1 regulatory pathway by azole and non-azole drugs.

Journal: mSphere
Published: November 18, 2024

Gene dosage and protein valency impact phase separation and fungal cell fate.

Gene dosage and protein valency impact phase separation and fungal cell fate.

Journal: PLoS genetics
Published: October 18, 2024
Showing 1-12 of 111

Last Updated: 09/26/2026