Damien Marsic

Suzhou Industrial Park
Suzhou, China

Last Updated: 09/26/2026

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Found 11 publications

Biodistribution and safety of a single rAAV3B-AAT vector for silencing and replacement of alpha-1 antitrypsin in Cynomolgus macaques.

Biodistribution and safety of a single rAAV3B-AAT vector for silencing and replacement of alpha-1 antitrypsin in Cynomolgus macaques.

Journal: Molecular therapy. Methods & clinical development

Published: September 12, 2023

Intravitreal injection of a rationally designed AAV capsid library in non-human primate identifies variants with enhanced retinal transduction and neutralizing antibody evasion.

Intravitreal injection of a rationally designed AAV capsid library in non-human primate identifies variants with enhanced retinal transduction and neutralizing antibody evasion.

Journal: Molecular therapy : the journal of the American Society of Gene Therapy

Published: August 23, 2023

Characterization of a Bioengineered AAV3B Capsid Variant with Enhanced Hepatocyte Tropism and Immune Evasion.

Characterization of a Bioengineered AAV3B Capsid Variant with Enhanced Hepatocyte Tropism and Immune Evasion.

Journal: Human gene therapy

Published: March 23, 2023

Identification of Novel Retinal Pericyte-Targeting rAAV Vectors Through Directed Evolution.

Identification of Novel Retinal Pericyte-Targeting rAAV Vectors Through Directed Evolution.

Journal: Translational vision science & technology

Published: August 26, 2022

Engineering and In Vitro Selection of a Novel AAV3B Variant with High Hepatocyte Tropism and Reduced Seroreactivity.

Engineering and In Vitro Selection of a Novel AAV3B Variant with High Hepatocyte Tropism and Reduced Seroreactivity.

Journal: Molecular therapy. Methods & clinical development

Published: June 04, 2020

Evaluation of engineered AAV capsids for hepatic factor IX gene transfer in murine and canine models.

Evaluation of engineered AAV capsids for hepatic factor IX gene transfer in murine and canine models.

Journal: Journal of translational medicine

Published: April 03, 2017

Direct Head-to-Head Evaluation of Recombinant Adeno-associated Viral Vectors Manufactured in Human versus Insect Cells.

Direct Head-to-Head Evaluation of Recombinant Adeno-associated Viral Vectors Manufactured in Human versus Insect Cells.

Journal: Molecular therapy : the journal of the American Society of Gene Therapy

Published: March 13, 2017

An Immune-Competent Murine Model to Study Elimination of AAV-Transduced Hepatocytes by Capsid-Specific CD8+ T Cells.

An Immune-Competent Murine Model to Study Elimination of AAV-Transduced Hepatocytes by Capsid-Specific CD8+ T Cells.

Journal: Molecular therapy. Methods & clinical development

Published: November 09, 2016

Altering Tropism of rAAV by Directed Evolution.

Altering Tropism of rAAV by Directed Evolution.

Journal: Methods in molecular biology (Clifton, N.J.)

Published: November 28, 2015

High-accuracy biodistribution analysis of adeno-associated virus variants by double barcode sequencing.

High-accuracy biodistribution analysis of adeno-associated virus variants by double barcode sequencing.

Journal: Molecular therapy. Methods & clinical development

Published: June 18, 2015

Vector design Tour de Force: integrating combinatorial and rational approaches to derive novel adeno-associated virus variants.

Vector design Tour de Force: integrating combinatorial and rational approaches to derive novel adeno-associated virus variants.

Journal: Molecular therapy : the journal of the American Society of Gene Therapy

Published: March 19, 2014

Showing 1-11 of 11

Last Updated: 09/26/2026