Dan Levy

Beersheba, D, Israel

Last Updated: 09/26/2026

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Found 34 publications

SETD6-mediated methylation of PPARγ establishes a transcriptional feedback circuit promoting lipid accumulation in liver-derived cells.

SETD6-mediated methylation of PPARγ establishes a transcriptional feedback circuit promoting lipid accumulation in liver-derived cells.

Journal: eLife

Published: August 28, 2026

Mechanisms of Substrate Recognition by the Multispecific Protein Lysine Methyltransferase SETD6.

Mechanisms of Substrate Recognition by the Multispecific Protein Lysine Methyltransferase SETD6.

Journal: Life (Basel, Switzerland)

Published: September 04, 2025

Machine learning-driven prediction of substrates for enzymes introducing or removing protein post-translational modifications.

Machine learning-driven prediction of substrates for enzymes introducing or removing protein post-translational modifications.

Journal: Communications chemistry

Published: August 04, 2025

RAD18 methylation by the methyltransferase SETD6 attenuates DNA breaks.

RAD18 methylation by the methyltransferase SETD6 attenuates DNA breaks.

Journal: Scientific reports

Published: May 05, 2025

SETD6 mediates selective interaction and genomic occupancy of BRD4 and MITF in melanoma cells.

SETD6 mediates selective interaction and genomic occupancy of BRD4 and MITF in melanoma cells.

Journal: NAR cancer

Published: March 05, 2025

E2F1 K117 methylation by SETD6 disrupts BRD4-E2F1 binding and modulates E2F1 chromatin binding and gene regulation in prostate cancer cells.

E2F1 K117 methylation by SETD6 disrupts BRD4-E2F1 binding and modulates E2F1 chromatin binding and gene regulation in prostate cancer cells.

Journal: Nucleic acids research

Published: February 24, 2025

ACTB methylation regulates SMARCA4 genomic occupancy to promote translation and reduce adhesion in colorectal cancer cells.

ACTB methylation regulates SMARCA4 genomic occupancy to promote translation and reduce adhesion in colorectal cancer cells.

Journal: Genome research

Published: February 16, 2025

A ciliopathy combining Joubert syndrome and Oro-Facial-Digital syndrome caused by bi-allelic 5'-UTR loss-of-function CEP83 variant.

A ciliopathy combining Joubert syndrome and Oro-Facial-Digital syndrome caused by bi-allelic 5'-UTR loss-of-function CEP83 variant.

Journal: NPJ genomic medicine

Published: November 24, 2024

Orchestrating epigenetics: a comprehensive review of the methyltransferase SETD6.

Orchestrating epigenetics: a comprehensive review of the methyltransferase SETD6.

Journal: Experimental & molecular medicine

Published: September 03, 2024

SUMO-mediated regulation of H3K4me3 reader SET-26 controls germline development in C. elegans.

SUMO-mediated regulation of H3K4me3 reader SET-26 controls germline development in C. elegans.

Journal: PLoS biology

Published: March 18, 2024

Distinct specificities of the HEMK2 protein methyltransferase in methylation of glutamine and lysine residues.

Distinct specificities of the HEMK2 protein methyltransferase in methylation of glutamine and lysine residues.

Journal: Protein science : a publication of the Protein Society

Published: October 18, 2023

Methylation of the transcription factor E2F1 by SETD6 regulates SETD6 expression via a positive feedback mechanism.

Methylation of the transcription factor E2F1 by SETD6 regulates SETD6 expression via a positive feedback mechanism.

Journal: The Journal of biological chemistry

Published: June 22, 2023

Showing 1-12 of 34

Last Updated: 09/26/2026